Gene Symbol | CLIC6 |
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Entrez Gene | 54102 |
Alt Symbol | CLIC1L |
Species | Human |
Gene Type | protein-coding |
Description | chloride intracellular channel 6 |
Other Description | chloride channel form A|chloride intracellular channel protein 6|parchorin |
Swissprots | Q8IX31 A8K0U8 Q96NY7 |
Accessions | EAX09775 EAX09776 Q96NY7 AF308293 AF426169 AAL24813 AF448438 AAN76729 AF448439 AAN76730 AK092733 BAC03959 AK289663 BAF82352 BC040196 AAH40196 BC169220 XM_011529650 XP_011527952 NM_053277 NP_444507 |
Function | May insert into membranes and form chloride ion channels. May play a critical role in water-secreting cells, possibly through the regulation of chloride ion transport (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000250}. Cell membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}. Note=Predominantly cytoplasmic. Upon chloride ion efflux from the cell, it is translocated to the plasma membrane (By similarity). {ECO:0000250}. |
Tissue Specificity | Expressed in brain, placenta, pancreas and liver. {ECO:0000269|PubMed:12226712}. |
CLIC6 CRISPR/Cas9 KO Plasmid (h) - sc-412265 from Santa Cruz Biotechnology
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CLIC6 HDR Plasmid (h) - sc-412265-HDR from Santa Cruz Biotechnology
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CLIC6 Double Nickase Plasmid (h) - sc-412265-NIC from Santa Cruz Biotechnology
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CLIC6 Double Nickase Plasmid (h2) - sc-412265-NIC-2 from Santa Cruz Biotechnology
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CLIC6 CRISPR Activation Plasmid (h) - sc-412265-ACT from Santa Cruz Biotechnology
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CLIC6 CRISPR Activation Plasmid (h2) - sc-412265-ACT-2 from Santa Cruz Biotechnology
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CLIC6 Lentiviral Activation Particles (h) - sc-412265-LAC from Santa Cruz Biotechnology
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CLIC6 Lentiviral Activation Particles (h2) - sc-412265-LAC-2 from Santa Cruz Biotechnology
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CLIC6 siRNA (h) - sc-62130 from Santa Cruz Biotechnology
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CLIC6 shRNA Plasmid (h) - sc-62130-SH from Santa Cruz Biotechnology
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CLIC6 shRNA (h) Lentiviral Particles - sc-62130-V from Santa Cruz Biotechnology
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CLIC6 RNAi - H00054102-R01 from Novus Biologicals
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MISSION® esiRNA - EHU068291 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN6233 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6233 from Sigma-Aldrich
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CLIC6 siRNA (Human) - CRJ0019 from Cohesion Biosciences
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CLIC6 - MBS8210889 from MyBioSource
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shRNA set against Human CLIC6 (NM_053277.1) - SHH265333 from Creative biogene
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shRNA set against Human CLIC6(NM_053277.1) - SHG182831 from Creative biogene
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Human CLIC6 siRNA - orb270520 from Biorbyt
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CLIC6 shRNA Plasmid (Human) - CHJ0019 from Cohesion Biosciences
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CLIC6 miRNA 3'UTR clone - MiUTR1H-02223 from Creative biogene
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