| Gene Symbol | UCK2 |
|---|---|
| Entrez Gene | 7371 |
| Alt Symbol | TSA903, UK, UMPK |
| Species | Human |
| Gene Type | protein-coding |
| Description | uridine-cytidine kinase 2 |
| Other Description | cytidine monophosphokinase 2|testis-specific protein TSA903|uridine kinase|uridine monophosphate kinase|uridine monophosphokinase 2 |
| Swissprots | Q9BU42 Q5VV91 Q96KG5 Q7KZV3 Q92528 Q9BZX2 |
| Accessions | CBN61306 CBN62649 CBN69656 EAW90767 EAW90768 EAW90769 Q9BZX2 AB062451 BAB56162 AF236637 AAK14053 AK294537 BAG57744 AK309739 BC002906 AAH02906 BM714864 BT006860 AAP35506 CR456857 CAG33138 D78335 BAA11349 DR762696 XM_011509969 XP_011508271 XM_011509970 XP_011508272 NM_012474 NP_036606 |
| Function | Phosphorylates uridine and cytidine to uridine monophosphate and cytidine monophosphate. Does not phosphorylate deoxyribonucleosides or purine ribonucleosides. Can use ATP or GTP as a phosphate donor. Can also phosphorylate cytidine and uridine nucleoside analogs such as 6-azauridine, 5-fluorouridine, 4- thiouridine, 5-bromouridine, N(4)-acetylcytidine, N(4)- benzoylcytidine, 5-fluorocytidine, 2-thiocytidine, 5- methylcytidine, and N(4)-anisoylcytidine. |
| Tissue Specificity | According to PubMed:8812458; testis-specific. According to PubMed:11306702, placenta-specific. {ECO:0000269|PubMed:8812458}. |
| Top Pathways | Drug metabolism - other enzymes, Pyrimidine metabolism |