| Gene Symbol |
UCK2
|
| Entrez Gene |
7371
|
| Alt Symbol |
TSA903, UK, UMPK
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
uridine-cytidine kinase 2
|
| Other Description |
cytidine monophosphokinase 2|testis-specific protein TSA903|uridine kinase|uridine monophosphate kinase|uridine monophosphokinase 2
|
| Swissprots |
Q9BU42 Q5VV91 Q96KG5 Q7KZV3 Q92528 Q9BZX2
|
| Accessions |
CBN61306 CBN62649 CBN69656 EAW90767 EAW90768 EAW90769 Q9BZX2 AB062451 BAB56162 AF236637 AAK14053 AK294537 BAG57744 AK309739 BC002906 AAH02906 BM714864 BT006860 AAP35506 CR456857 CAG33138 D78335 BAA11349 DR762696 XM_011509969 XP_011508271 XM_011509970 XP_011508272 NM_012474 NP_036606
|
| Function |
Phosphorylates uridine and cytidine to uridine monophosphate and cytidine monophosphate. Does not phosphorylate deoxyribonucleosides or purine ribonucleosides. Can use ATP or GTP as a phosphate donor. Can also phosphorylate cytidine and uridine nucleoside analogs such as 6-azauridine, 5-fluorouridine, 4- thiouridine, 5-bromouridine, N(4)-acetylcytidine, N(4)- benzoylcytidine, 5-fluorocytidine, 2-thiocytidine, 5- methylcytidine, and N(4)-anisoylcytidine.
|
| Tissue Specificity |
According to PubMed:8812458; testis-specific. According to PubMed:11306702, placenta-specific. {ECO:0000269|PubMed:8812458}.
|
| Top Pathways |
Drug metabolism - other enzymes, Pyrimidine metabolism
|
