| Gene Symbol |
TUBA1A
|
| Entrez Gene |
7846
|
| Alt Symbol |
B-ALPHA-1, LIS3, TUBA3
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
tubulin, alpha 1a
|
| Other Description |
hum-a-tub1|hum-a-tub2|tubulin B-alpha-1|tubulin alpha-1A chain|tubulin alpha-3 chain|tubulin, alpha, brain-specific
|
| Swissprots |
P04687 G3V1U9 Q71U36 P05209 A8K0B8
|
| Accessions |
CAA25855 EAW58052 EAW58053 EAW58054 EAW58055 Q71U36 AF141347 AAD33871 AF141348 AAD33872 AK057842 AK289483 BAF82172 AK297775 BAG60120 AK298838 BAG60966 AU136397 BC006468 AAH06468 BC050637 AAH50637 BC057823 DA117857 DC340080 DQ890579 ABM92196 EU176481 ABW03282 K00557 AAA91575 NM_001270399 NP_001257328 NM_001270400 NP_001257329 NM_006009 NP_006000
|
| Function |
Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.
|
| Subcellular Location |
Cytoplasm, cytoskeleton.
|
| Tissue Specificity |
Expressed at a high level in fetal brain. {ECO:0000269|PubMed:17584854}.
|
| Top Pathways |
Gap junction, Pathogenic Escherichia coli infection, Phagosome
|