Gene Symbol | TUBA1A |
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Entrez Gene | 7846 |
Alt Symbol | B-ALPHA-1, LIS3, TUBA3 |
Species | Human |
Gene Type | protein-coding |
Description | tubulin, alpha 1a |
Other Description | hum-a-tub1|hum-a-tub2|tubulin B-alpha-1|tubulin alpha-1A chain|tubulin alpha-3 chain|tubulin, alpha, brain-specific |
Swissprots | P04687 G3V1U9 Q71U36 P05209 A8K0B8 |
Accessions | CAA25855 EAW58052 EAW58053 EAW58054 EAW58055 Q71U36 AF141347 AAD33871 AF141348 AAD33872 AK057842 AK289483 BAF82172 AK297775 BAG60120 AK298838 BAG60966 AU136397 BC006468 AAH06468 BC050637 AAH50637 BC057823 DA117857 DC340080 DQ890579 ABM92196 EU176481 ABW03282 K00557 AAA91575 NM_001270399 NP_001257328 NM_001270400 NP_001257329 NM_006009 NP_006000 |
Function | Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. |
Subcellular Location | Cytoplasm, cytoskeleton. |
Tissue Specificity | Expressed at a high level in fetal brain. {ECO:0000269|PubMed:17584854}. |
Top Pathways | Gap junction, Pathogenic Escherichia coli infection, Phagosome |
α Tubulin siRNA (h) - sc-29188 from Santa Cruz Biotechnology
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α Tubulin shRNA Plasmid (h) - sc-29188-SH from Santa Cruz Biotechnology
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α Tubulin shRNA (h) Lentiviral Particles - sc-29188-V from Santa Cruz Biotechnology
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α Tubulin siRNA (h2) - sc-44242 from Santa Cruz Biotechnology
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α Tubulin shRNA Plasmid (h2) - sc-44242-SH from Santa Cruz Biotechnology
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α Tubulin shRNA (h2) Lentiviral Particles - sc-44242-V from Santa Cruz Biotechnology
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α1a Tubulin CRISPR/Cas9 KO Plasmid (h) - sc-400022 from Santa Cruz Biotechnology
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α1a Tubulin HDR Plasmid (h) - sc-400022-HDR from Santa Cruz Biotechnology
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α1a Tubulin Double Nickase Plasmid (h) - sc-400022-NIC from Santa Cruz Biotechnology
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α1a Tubulin Double Nickase Plasmid (h2) - sc-400022-NIC-2 from Santa Cruz Biotechnology
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α1a Tubulin CRISPR Activation Plasmid (h) - sc-400022-ACT from Santa Cruz Biotechnology
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α1a Tubulin CRISPR Activation Plasmid (h2) - sc-400022-ACT-2 from Santa Cruz Biotechnology
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α1a Tubulin Lentiviral Activation Particles (h) - sc-400022-LAC from Santa Cruz Biotechnology
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α1a Tubulin Lentiviral Activation Particles (h2) - sc-400022-LAC-2 from Santa Cruz Biotechnology
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alpha Tubulin RNAi - H00007846-R01 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN2319 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2319 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR00878 from Sigma-Aldrich
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TUBA1A siRNA (Human) - CRH5292 from Cohesion Biosciences
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TUBA1A - MBS8237963 from MyBioSource
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α1a Tubulin CRISPR/Cas9 KO Plasmid (h2) - sc-400022-KO-2 from Santa Cruz Biotechnology
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α1a Tubulin HDR Plasmid (h2) - sc-400022-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human Tuba1a (NM_006009.3) - SHH437584 from Creative biogene
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Human TUBA1A siRNA - orb265794 from Biorbyt
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TUBA1A shRNA Plasmid (Human) - CHH5292 from Cohesion Biosciences
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