| Gene Symbol |
AK5
|
| Entrez Gene |
26289
|
| Alt Symbol |
AK6
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
adenylate kinase 5
|
| Other Description |
AK 5|ATP-AMP transphosphorylase 5|adenylate kinase 6|adenylate kinase isoenzyme 5
|
| Swissprots |
Q8N464 Q6FH66 Q96EC9 Q7Z4T5 Q5U622 Q9Y6K8 Q86YS0
|
| Accessions |
EAX06377 EAX06378 EAX06379 Q9Y6K8 AF062595 AAD27956 AF445193 AAP97322 AK090967 BAC03558 AW665223 AY171600 AAO16520 BC012467 AAH12467 BC033896 AAH33896 BC036666 AAH36666 CR541890 CAG46688 DN993295 XM_005270739 XP_005270796 XM_006710572 XP_006710635 NM_012093 NP_036225 NM_174858 NP_777283
|
| Function |
Nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Active on AMP and dAMP with ATP as a donor. When GTP is used as phosphate donor, the enzyme phosphorylates AMP, CMP, and to a small extent dCMP. Also displays broad nucleoside diphosphate kinase activity. {ECO:0000269|PubMed:19647735, ECO:0000269|PubMed:23416111}.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:19647735}.
|
| Tissue Specificity |
Brain specific.
|
| Top Pathways |
Purine metabolism
|