Gene Symbol | AK5 |
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Entrez Gene | 26289 |
Alt Symbol | AK6 |
Species | Human |
Gene Type | protein-coding |
Description | adenylate kinase 5 |
Other Description | AK 5|ATP-AMP transphosphorylase 5|adenylate kinase 6|adenylate kinase isoenzyme 5 |
Swissprots | Q8N464 Q6FH66 Q96EC9 Q7Z4T5 Q5U622 Q9Y6K8 Q86YS0 |
Accessions | EAX06377 EAX06378 EAX06379 Q9Y6K8 AF062595 AAD27956 AF445193 AAP97322 AK090967 BAC03558 AW665223 AY171600 AAO16520 BC012467 AAH12467 BC033896 AAH33896 BC036666 AAH36666 CR541890 CAG46688 DN993295 XM_005270739 XP_005270796 XM_006710572 XP_006710635 NM_012093 NP_036225 NM_174858 NP_777283 |
Function | Nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Active on AMP and dAMP with ATP as a donor. When GTP is used as phosphate donor, the enzyme phosphorylates AMP, CMP, and to a small extent dCMP. Also displays broad nucleoside diphosphate kinase activity. {ECO:0000269|PubMed:19647735, ECO:0000269|PubMed:23416111}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:19647735}. |
Tissue Specificity | Brain specific. |
Top Pathways | Purine metabolism |
AK5 CRISPR/Cas9 KO Plasmid (h) - sc-411909 from Santa Cruz Biotechnology
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AK5 HDR Plasmid (h) - sc-411909-HDR from Santa Cruz Biotechnology
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AK5 Double Nickase Plasmid (h) - sc-411909-NIC from Santa Cruz Biotechnology
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AK5 Double Nickase Plasmid (h2) - sc-411909-NIC-2 from Santa Cruz Biotechnology
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AK5 CRISPR Activation Plasmid (h) - sc-411909-ACT from Santa Cruz Biotechnology
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AK5 CRISPR Activation Plasmid (h2) - sc-411909-ACT-2 from Santa Cruz Biotechnology
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AK5 Lentiviral Activation Particles (h) - sc-411909-LAC from Santa Cruz Biotechnology
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AK5 Lentiviral Activation Particles (h2) - sc-411909-LAC-2 from Santa Cruz Biotechnology
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AK5 siRNA (h) - sc-72059 from Santa Cruz Biotechnology
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AK5 shRNA Plasmid (h) - sc-72059-SH from Santa Cruz Biotechnology
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AK5 shRNA (h) Lentiviral Particles - sc-72059-V from Santa Cruz Biotechnology
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AK5 RNAi - H00026289-R04 from Novus Biologicals
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AK5 RNAi - H00026289-R03 from Novus Biologicals
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MISSION® esiRNA - EHU076391 from Sigma-Aldrich
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MISSION® siRNA - SIHK0085 from Sigma-Aldrich
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MISSION® siRNA - SIHK0086 from Sigma-Aldrich
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MISSION® siRNA - SIHK0087 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN2998 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2998 from Sigma-Aldrich
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AK5 siRNA (Human) - CRH8808 from Cohesion Biosciences
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AK5 - MBS8240617 from MyBioSource
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shRNA set against Human AK5 (NM_174858.2) - SHH234130 from Creative biogene
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Human AK5 siRNA - orb269310 from Biorbyt
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AK5 shRNA Plasmid (Human) - CHH8808 from Cohesion Biosciences
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AK5 miRNA 3'UTR clone - MiUTR3H-09659 from Creative biogene
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