UNKL

Gene Symbol UNKL
Entrez Gene 64718
Alt Symbol C16orf28, ZC3H5L, ZC3HDC5L
Species Human
Gene Type protein-coding
Description unkempt family zinc finger-like
Other Description RING finger protein unkempt-like|putative E3 ubiquitin-protein ligase UNKL|unkempt homolog-like|zinc finger CCCH domain-containing protein 5-like
Swissprots Q96RZ1 B0QYN6 Q96EV1 Q9H5K0 Q9BWL5 B1GXI8 Q9H9P5 Q9UJJ8
Accessions AAK61278 AAK61279 EAW85659 EAW85660 EAW85661 EAW85662 EAW85663 EAW85664 Q9H9P5 AK022685 BAB14178 AK024842 AK027013 BAB15626 AK124977 AM944365 CAQ16184 AW971542 BC000150 AAH00150 BC011924 AAH11924 BI751989 BM763288 BQ776895 BU431187 BU633778 CB988960 CF136587 DA558634 DA739764 HY086058 XM_005255505 XP_005255562 XM_011522610 XP_011520912 XM_011522611 XP_011520913 XM_011522612 XP_011520914 XM_011522613 XP_011520915 XR_932901 NM_001037125 NP_001032202 NM_001193388 NP_001180317 NM_001193389 NP_001180318 NM_001276414 NP_001263343 NM_023076
Function May participate in a protein complex showing an E3 ligase activity regulated by RAC1. Ubiquitination is directed towards itself and possibly other substrates, such as SMARCD2/BAF60b. Intrinsic E3 ligase activity has not been proven. {ECO:0000269|PubMed:20148946}.
Subcellular Location Isoform 4: Cytoplasm. Nucleus. Note=Isoform 4 is primarily localized in the cytoplasm but has the ability to shuttle between the nucleus and the cytoplasm.

UNKL (F-8) - sc-398716 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
UNKL (F-8): sc-398716. Western blot analysis of UNKL expression in JAR (A) and JEG-3 (B) whole cell lysates.

UNKL (E-12) - sc-138715 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

UNKL (S-12) - sc-138717 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-RING finger protein unkempt like antibody - ab130603 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-RING finger protein unkempt like antibody (ab130603) at 1/100 dilution + A549 cell line lysate at 35 µg

Anti-RING finger protein unkempt like antibody - ab68731 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-RING finger protein unkempt like antibody (ab68731) at 1/500 dilutionLane 1 : RING finger protein unkempt like transfected 293T cell lysateLane 2 : Non transfected 293T cell lysateLysates/proteins at 25 µg per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

Anti-RING finger protein unkempt like antibody - N-terminal - ab155197 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-RING finger protein unkempt like antibody - N-terminal (ab155197) at 1/1000 dilution + HeLa whole cell lysate at 30 µg

Anti-UNKL Antibody (aa1-30, AP) - LS-C273064 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UNKL Antibody (aa1-30, APC) - LS-C273065 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UNKL Antibody (aa1-30, Biotin) - LS-C273066 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UNKL Antibody (aa1-30, FITC) - LS-C273067 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UNKL Antibody (aa1-30, Azide-free, HRP) - LS-C273068 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UNKL Antibody (aa1-30, PE) - LS-C273069 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UNKL Antibody (aa1-30) - LS-C326203 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UNKL Antibody (aa1-30) - LS-C157329 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot of UNKL (arrow) using rabbit polyclonal UNKL Antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the UNKL gene.

UNKL Antibody - NBP2-33766 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

UNKL Antibody - NBP2-15156 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

UNKL Antibody - H00064718-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: UNKL Antibody [H00064718-B01P] - Analysis of UNKL expression in transfected 293T cell line by UNKL polyclonal antibody. Lane 1: UNKL transfected lysate(30.47 KDa). Lane 2: Non-transfected lysate.

UNKL Antibody - H00064718-B02 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal

UNKL Antibody - H00064718-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal

Anti-UNKL antibody produced in mouse - SAB1407892 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-UNKL: <B>Cat. No. SAB1407892</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~30.5 kDa using UNKL transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

Anti-UNKL (N antibody produced in rabbit - SAB2701459 from Sigma-Aldrich

Prices $326.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Anti-UNKL (N-terminal): <B>Cat. No. SAB2701459</B>: Immunofluorescence analysis of methanol-fixed HeLa, using UNKL antibody at 1:500 dilution.

Anti-UNKL (108-120) antibody produced in rabbit - SAB1102373 from Sigma-Aldrich

Prices $298.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Lysate of HEK-293T cells overexpressing human UNKL was separated on SDS-PAGE, blotted with Anti-UNKL (108-120) (<B>Cat. No. SAB1102373</B>) and developed using Goat Anti-Rabbit IgG-Peroxidase (<B>Cat. No. A0545</B>) and a chemiluminescent substrate. <BR/><B>Lanes</B><BR/>1. Antibody dilution 1:1,000 <BR/>2. Antibody dilution 1:1,000 + UNKL immunizing peptide (human, 108-120)

Anti-UNKL antibody produced in rabbit - HPA055801 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-UNKL: <B>Cat. No. HPA055801</B>: Immunohistochemical staining of Human colon shows moderate membranous and cytoplasmic positivity in glandular cells.

UNKL-Antibody-N-term - AP17288a from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
UNKL Antibody (N-term) (Cat. #AP17288a) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the UNKL antibody detected the UNKL protein (arrow).

UNKL Antibody - N-terminal region (OAAB12719) - OAAB12719 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
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