| Gene Symbol |
UNKL
|
| Entrez Gene |
64718
|
| Alt Symbol |
C16orf28, ZC3H5L, ZC3HDC5L
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
unkempt family zinc finger-like
|
| Other Description |
RING finger protein unkempt-like|putative E3 ubiquitin-protein ligase UNKL|unkempt homolog-like|zinc finger CCCH domain-containing protein 5-like
|
| Swissprots |
Q96RZ1 B0QYN6 Q96EV1 Q9H5K0 Q9BWL5 B1GXI8 Q9H9P5 Q9UJJ8
|
| Accessions |
AAK61278 AAK61279 EAW85659 EAW85660 EAW85661 EAW85662 EAW85663 EAW85664 Q9H9P5 AK022685 BAB14178 AK024842 AK027013 BAB15626 AK124977 AM944365 CAQ16184 AW971542 BC000150 AAH00150 BC011924 AAH11924 BI751989 BM763288 BQ776895 BU431187 BU633778 CB988960 CF136587 DA558634 DA739764 HY086058 XM_005255505 XP_005255562 XM_011522610 XP_011520912 XM_011522611 XP_011520913 XM_011522612 XP_011520914 XM_011522613 XP_011520915 XR_932901 NM_001037125 NP_001032202 NM_001193388 NP_001180317 NM_001193389 NP_001180318 NM_001276414 NP_001263343 NM_023076
|
| Function |
May participate in a protein complex showing an E3 ligase activity regulated by RAC1. Ubiquitination is directed towards itself and possibly other substrates, such as SMARCD2/BAF60b. Intrinsic E3 ligase activity has not been proven. {ECO:0000269|PubMed:20148946}.
|
| Subcellular Location |
Isoform 4: Cytoplasm. Nucleus. Note=Isoform 4 is primarily localized in the cytoplasm but has the ability to shuttle between the nucleus and the cytoplasm.
|