PXN

Gene Symbol PXN
Entrez Gene 5829
Alt Symbol -
Species Human
Gene Type protein-coding
Description paxillin
Other Description -
Swissprots O14970 P49023 Q5HYA4 O60360 B2RAI3 B7ZMB4 O14971
Accessions AAC05175 AAD00648 EAW98175 EAW98176 EAW98177 EAW98178 EAW98179 P49023 AA922640 AB209034 BAD92271 AK026695 BAB15529 AK122964 BAG53822 AK128712 BAC87586 AK298057 BAG60351 AK299486 BAG61448 AK314204 BAG36880 BC003647 AAH03647 BC006840 BC010498 BC015217 BC052611 AAH52611 BC136787 AAI36788 BC136794 AAI36795 BC144410 AAI44411 BM742662 BU500419 BX648777 CAI46024 D86862 BAA18997 D86863 BAA18998 DA105135 DA565031 DB472926 U14588 AAC50104 XM_005253910 XP_005253967 XM_005253912 XP_005253969 XM_005253913 XP_005253970 XM_005253914 XP_005253971 XM_005253915 XP_005253972 XM_005253916 XP_005253973 XM_005253917 XP_005253974 XM_006719531 XP_006719594 XM_006719532 XP_006719595 XM_006719533 XP_006719596 XM_006719534 XP_006719597 XM_006719535 XP_006719598 XM_006719536 XP_006719599 XM_006719537 XP_006719600 XM_006719538 XP_006719601 XM_006719539 XP_006719602 XM_011538617 XP_011536919 XM_011538618 XP_011536920 XM_011538619 XP_011536921 XM_011538620 XP_011536922 XM_011538621 XP_011536923 XM_011538622 XP_011536924 XM_011538623 XP_011536925 XM_011538624 XP_011536926 XM_011538625 XP_011536927 XM_011538626 XP_011536928 XM_011538627 XP_011536929 XR_944654 NM_001080855 NP_001074324 NM_001243756 NP_001230685 NM_002859 NP_002850 NM_025157 NP_079433
Function Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion).
Subcellular Location Cytoplasm, cytoskeleton {ECO:0000269|PubMed:20489202}. Cell junction, focal adhesion {ECO:0000269|PubMed:20489202}. Cytoplasm, cell cortex {ECO:0000250}. Note=Colocalizes with integrins at the cell periphery. {ECO:0000250}.
Top Pathways VEGF signaling pathway, Focal adhesion, Leukocyte transendothelial migration, Chemokine signaling pathway, Bacterial invasion of epithelial cells

Phospho-Paxillin (Tyr118) Antibody - 2541 from Cell Signaling Technology

Prices $287.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of untreated and lambda-phosphatase treated COS cells, using Phospho-Paxillin (Tyr118) Antibody (left) and Paxillin Antibody #2542 (right).

Paxillin Antibody - 2542 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from various cell lines, using Paxillin Antibody.

Paxillin (D9G12) Rabbit mAb - 12065 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D9G12
Western blot analysis of extracts from various cell lines using Paxillin (D9G12) Rabbit mAb. The 45 kDa band is a degradation product of full-length paxillin protein.

paxillin (B-2) - sc-365379 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
paxillin (B-2): sc-365379. Western blot analysis of paxillin expression in CCD-1064Sk whole cell lysate.

paxillin (C-1) - sc-373880 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
paxillin (C-1): sc-373880. Western blot analysis of paxillin expression in HISM (A), ECV304 (B) and CCD-1064Sk (C) whole cell lysates.

paxillin (A-5) - sc-390738 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
paxillin (A-5): sc-390738. Western blot analysis of paxillin expression in CCD-1064Sk (A) and HeLa (B) whole cell lysates.

paxillin (C-10) - sc-393149 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
paxillin (C-10): sc-393149. Western blot analysis of paxillin expression in CCD-1064Sk (A) and HeLa (B) whole cell lysates.

paxillin (C-18) - sc-7336 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

paxillin (D-8) - sc-365059 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
paxillin (D-8): sc-365059. Western blot analysis of paxillin expression in CCD-1064Sk whole cell lysate.

paxillin (D-9) - sc-365174 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
paxillin (D-9): sc-365174. Western blot analysis of paxillin expression in CCD-1064Sk whole cell lysate.

paxillin (H-114) - sc-5574 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
paxillin (H-114): sc-5574. Western blot analysis of paxillin expression in CCD-1064Sk (A) and HISM (B) whole cell lysates.

paxillin (I-18) - sc-31009 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
paxillin (I-18): sc-31009. Western blot analysis of paxillin expression in CCD-1064Sk whole cell lysate.

paxillin (K-20) - sc-31008 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
paxillin (K-20): sc-31008. Western blot analysis of paxillin expression in ECV304 whole cell lysate.

paxillin (T-16) - sc-31010 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
paxillin (T-16): sc-31010. Western blot analysis of paxillin expression in ECV304 whole cell lysate.

paxillin (177) - sc-136297 from Santa Cruz Biotechnology

Prices $279.00
Sizes 50 µg/0.5 ml
Host Mouse
Clonality Monoclonal
paxillin (177): sc-136297. Western blot analysis of paxillin expression in human endothelial whole cell lysate.

p-paxillin (A-5) - sc-365020 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Sodium Orthovanadate: sc-3540 + Hydrogen Peroxide: sc-20336. Western blot analysis of paxillin phosphorylation in untreated (A), pervanadate treated (B) and pervanadate and lambda protein phosphatase (sc-200312A) treated (C) A-431 whole cell lysates. Antibody tested: p-paxillin (A-5): sc-365020 (A,B,C).

p-paxillin (D-10) - sc-271980 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Western blot analysis of paxillin phosphorylation in untreated (A), pervanadate treated (B) and pervanadate and lambda protein phosphatase (sc-200312A) treated (C) A-431 whole cell lysates. Antibodies tested include p-paxillin (D-10): sc-271980 (A,B,C).

p-paxillin (Tyr 118) - sc-14036 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
p-paxillin (Tyr 118)-R: sc-14036-R. Western blot analysis of paxillin phosphorylation in untreated (A), pervanadate treated (B) and pervanadate and lambda protein phosphatase (sc-200312A) treated (C) A-431 whole cell lysates.

p-paxillin (Tyr 118) - sc-101774 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
p-paxillin (Tyr 118): sc-101774. Western blot analysis of phosphorylated paxillin expression in untreated (A) and EGF-treated (B) HeLa whole cell lysates.

p-paxillin (Tyr 181) - sc-16668 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Western blot analysis of human recombinant paxillin fusion protein (A,C,E) and human recombinant paxillin phosphorylated by mouse recombinant Abl (B,D,F). Antibodies tested include paxilli fusion protein (H-114): sc-5574 (A,B), p-paxillin (Tyr 181): sc-16668 (C,D) and p-paxillin (Tyr 181)-R: sc-16668-R (E,F).

p-paxillin (Tyr 88) - sc-293114 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
p-paxillin (Tyr 88): sc-293114. Western blot analysis of paxillin phosphorylation expression in untreated (A) and EGF treated (B) HT29 whole cell lysates.

Anti-Paxillin (phospho S178) antibody - ab193677 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Paxillin (phospho S178) antibody (ab193677) at 1/500 dilutionLane 1 : Extracts from HT29 cellsLane 2 : Extracts from HT29 cells with antigen specific peptide

Anti-Paxillin (phospho Y118) antibody - ab75740 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
ab75740 at 1/50 dilution staining Paxillin in human breast carcinoma by Immunohistochemistry using paraffin-embedded tissue, in the absence or presence of the immunising phosphopeptide.

Anti-Paxillin (phospho Y118) antibody - ab194738 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Lane 1 : Anti-Paxillin (phospho Y118) antibody (ab194738) at 1/500 dilutionLane 2 : Anti-Paxillin (phospho Y118) antibody (ab194738) at 500 cellsLane 1 : Untreated 3T3 cell extractsLane 2 : 3T3 cell extracts treated by serum

Anti-Paxillin (phospho Y118) antibody - ab195911 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Paxillin (phospho Y118) antibody (ab195911) at 1/500 dilutionLane 1 : EGF treated HeLa whole cell lysates with antigen specific peptideLane 2 : EGF treated HeLa whole cell lysatesLysates/proteins at 12.5 µg per lane.
Search more