Gene Symbol |
PXN
|
Entrez Gene |
5829
|
Alt Symbol |
-
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
paxillin
|
Other Description |
-
|
Swissprots |
O14970 P49023 Q5HYA4 O60360 B2RAI3 B7ZMB4 O14971
|
Accessions |
AAC05175 AAD00648 EAW98175 EAW98176 EAW98177 EAW98178 EAW98179 P49023 AA922640 AB209034 BAD92271 AK026695 BAB15529 AK122964 BAG53822 AK128712 BAC87586 AK298057 BAG60351 AK299486 BAG61448 AK314204 BAG36880 BC003647 AAH03647 BC006840 BC010498 BC015217 BC052611 AAH52611 BC136787 AAI36788 BC136794 AAI36795 BC144410 AAI44411 BM742662 BU500419 BX648777 CAI46024 D86862 BAA18997 D86863 BAA18998 DA105135 DA565031 DB472926 U14588 AAC50104 XM_005253910 XP_005253967 XM_005253912 XP_005253969 XM_005253913 XP_005253970 XM_005253914 XP_005253971 XM_005253915 XP_005253972 XM_005253916 XP_005253973 XM_005253917 XP_005253974 XM_006719531 XP_006719594 XM_006719532 XP_006719595 XM_006719533 XP_006719596 XM_006719534 XP_006719597 XM_006719535 XP_006719598 XM_006719536 XP_006719599 XM_006719537 XP_006719600 XM_006719538 XP_006719601 XM_006719539 XP_006719602 XM_011538617 XP_011536919 XM_011538618 XP_011536920 XM_011538619 XP_011536921 XM_011538620 XP_011536922 XM_011538621 XP_011536923 XM_011538622 XP_011536924 XM_011538623 XP_011536925 XM_011538624 XP_011536926 XM_011538625 XP_011536927 XM_011538626 XP_011536928 XM_011538627 XP_011536929 XR_944654 NM_001080855 NP_001074324 NM_001243756 NP_001230685 NM_002859 NP_002850 NM_025157 NP_079433
|
Function |
Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion).
|
Subcellular Location |
Cytoplasm, cytoskeleton {ECO:0000269|PubMed:20489202}. Cell junction, focal adhesion {ECO:0000269|PubMed:20489202}. Cytoplasm, cell cortex {ECO:0000250}. Note=Colocalizes with integrins at the cell periphery. {ECO:0000250}.
|
Top Pathways |
VEGF signaling pathway, Focal adhesion, Leukocyte transendothelial migration, Chemokine signaling pathway, Bacterial invasion of epithelial cells
|