| Gene Symbol |
SEC11C
|
| Entrez Gene |
90701
|
| Alt Symbol |
SEC11L3, SPC21, SPCS4C
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
SEC11 homolog C (S. cerevisiae)
|
| Other Description |
SEC11-like 3|SEC11-like protein 3|SPase 21 kDa subunit|microsomal signal peptidase 21 kDa subunit|signal peptidase complex catalytic subunit SEC11C
|
| Swissprots |
B2RAA3 Q9BY50
|
| Accessions |
EAW63089 EAW63090 Q9BY50 AF212233 AAK14919 AK295346 BAG58315 AK307127 AK311213 AK314107 BAG36800 BC009703 AAH09703 BM760252 BM789622 BQ417397 HQ448732 ADQ33210 XM_005266779 XP_005266836 XM_011526260 XP_011524562 NM_001307941 NP_001294870 NM_033280 NP_150596
|
| Function |
Component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. {ECO:0000250}.
|
| Subcellular Location |
Microsome membrane {ECO:0000250}; Single- pass type II membrane protein {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
|
| Top Pathways |
Protein export
|
![Western Blot: SEC11C Overexpression Lysate (Adult Normal) [NBL1-15773] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for SEC11C.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/11991_SEC11C%2520Overexpression%2520Lysate%2520%2528Adult%2520Normal%2529-Western%2520Blot-NBL1-15773-img0002.jpg)