Gene Symbol | SEC11C |
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Entrez Gene | 90701 |
Alt Symbol | SEC11L3, SPC21, SPCS4C |
Species | Human |
Gene Type | protein-coding |
Description | SEC11 homolog C (S. cerevisiae) |
Other Description | SEC11-like 3|SEC11-like protein 3|SPase 21 kDa subunit|microsomal signal peptidase 21 kDa subunit|signal peptidase complex catalytic subunit SEC11C |
Swissprots | B2RAA3 Q9BY50 |
Accessions | EAW63089 EAW63090 Q9BY50 AF212233 AAK14919 AK295346 BAG58315 AK307127 AK311213 AK314107 BAG36800 BC009703 AAH09703 BM760252 BM789622 BQ417397 HQ448732 ADQ33210 XM_005266779 XP_005266836 XM_011526260 XP_011524562 NM_001307941 NP_001294870 NM_033280 NP_150596 |
Function | Component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. {ECO:0000250}. |
Subcellular Location | Microsome membrane {ECO:0000250}; Single- pass type II membrane protein {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. |
Top Pathways | Protein export |
SEC11C CRISPR/Cas9 KO Plasmid (h) - sc-409448 from Santa Cruz Biotechnology
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SEC11C HDR Plasmid (h) - sc-409448-HDR from Santa Cruz Biotechnology
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SEC11C Double Nickase Plasmid (h) - sc-409448-NIC from Santa Cruz Biotechnology
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SEC11C Double Nickase Plasmid (h2) - sc-409448-NIC-2 from Santa Cruz Biotechnology
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SEC11C CRISPR Activation Plasmid (h) - sc-409448-ACT from Santa Cruz Biotechnology
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SEC11C CRISPR Activation Plasmid (h2) - sc-409448-ACT-2 from Santa Cruz Biotechnology
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SEC11C Lentiviral Activation Particles (h) - sc-409448-LAC from Santa Cruz Biotechnology
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SEC11C Lentiviral Activation Particles (h2) - sc-409448-LAC-2 from Santa Cruz Biotechnology
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SEC11C siRNA (h) - sc-76464 from Santa Cruz Biotechnology
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SEC11C shRNA Plasmid (h) - sc-76464-SH from Santa Cruz Biotechnology
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SEC11C shRNA (h) Lentiviral Particles - sc-76464-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU010571 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN19018 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19018 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR00638 from Sigma-Aldrich
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SEC11C siRNA (Human) - CRJ3979 from Cohesion Biosciences
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SEC11C - MBS8214575 from MyBioSource
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shRNA set against Human SEC11C (NM_033280.2) - SHH403624 from Creative biogene
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shRNA set against Human SEC11C(NM_033280.2) - SHR211326 from Creative biogene
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Human SEC11C siRNA - orb274480 from Biorbyt
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SEC11C shRNA Plasmid (Human) - CHJ3979 from Cohesion Biosciences
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SEC11C miRNA 3'UTR clone - MiUTR1H-09226 from Creative biogene
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