| Gene Symbol |
AHSP
|
| Entrez Gene |
51327
|
| Alt Symbol |
EDRF, ERAF
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
alpha hemoglobin stabilizing protein
|
| Other Description |
alpha hemoglobin stabilising protein|alpha-hemoglobin-stabilizing protein|erythroid associated factor|erythroid differentiation associated factor|erythroid differentiation-related factor|erythroid-associated factor
|
| Swissprots |
Q8TD01 Q9NZD4
|
| Accessions |
AAL82894 AAO49381 EAW52118 Q9NZD4 AF112995 AAP97228 AF147435 AF208865 AAF64279 AF364517 AAK50856 BC035842 AAH35842 DQ890925 ABM81851 DQ894076 ABM85002 H94920 XM_005255351 XP_005255408 XM_005255352 XP_005255409 NM_016633 NP_057717
|
| Function |
Acts as a chaperone to prevent the harmful aggregation of alpha-hemoglobin during normal erythroid cell development. Specifically protects free alpha-hemoglobin from precipitation. It is predicted to modulate pathological states of alpha-hemoglobin excess such as beta-thalassemia. {ECO:0000269|PubMed:12066189}.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:12066189}.
|
| Tissue Specificity |
Expressed in blood and bone marrow. {ECO:0000269|PubMed:11231637, ECO:0000269|PubMed:12066189}.
|