| Gene Symbol |
NCDN
|
| Entrez Gene |
23154
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
neurochondrin
|
| Other Description |
-
|
| Swissprots |
Q9UBY2 Q9UBB6 Q9Y4D9 D3DPR9 Q9Y4A6
|
| Accessions |
AAD05029 BAA77830 BAA77831 EAX07410 EAX07411 EAX07412 Q9UBB6 AB011179 BAA25533 AB018739 BAA85384 AB018740 BAA85385 AK293658 BAG57106 AK295979 BAG58754 AL536768 AW207151 BC024592 AAH24592 BI545092 DQ891150 ABM82076 DQ894330 ABM85256 NM_001014839 NP_001014839 NM_001014841 NP_001014841 NM_014284 NP_055099
|
| Function |
Probably involved in signal transduction, in the nervous system, via increasing cell surface localization of GRM5 and positively regulating its signaling (By similarity). Required for the spatial learning process. Acts as a negative regulator of Ca(2+)-calmodulin-dependent protein kinase 2 (CaMK2) phosphorylation. May play a role in modulating melanin- concentrating hormone-mediated functions via its interaction with MCHR1 that interferes with G protein-coupled signal transduction. May be involved in bone metabolism. May also be involved in neurite outgrowth. {ECO:0000250, ECO:0000269|PubMed:16945926}.
|
| Subcellular Location |
Cytoplasm, cytosol. Cell projection, dendrite. Note=Localizes to somatic regions of neurons.
|
| Tissue Specificity |
Abundantly expressed in whole adult brain and in all individual brain regions examined, including spinal cord. Weakly expressed in ovary, testis, fetal brain and small intestine. {ECO:0000269|PubMed:10524216, ECO:0000269|PubMed:9628581}.
|
