Gene Symbol | TFDP3 |
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Entrez Gene | 51270 |
Alt Symbol | CT30, DP4, HCA661 |
Species | Human |
Gene Type | protein-coding |
Description | transcription factor Dp family, member 3 |
Other Description | E2F-like protein|cancer/testis antigen 30|hepatocellular carcinoma-associated antigen 661|transcription factor Dp family member 3 |
Swissprots | Q5H9I0 Q6DK49 Q9NZ54 |
Accessions | EAX11773 Q5H9I0 AF219119 AAF37562 BC074762 BC117336 BC126361 EU446842 ABZ92371 NM_016521 NP_057605 |
Function | Competitive inhibitor of E2F-mediated transactivation activity. Impairs E2F-mediated cell-cycle progression from G(1) to S phase. {ECO:0000269|PubMed:16418725, ECO:0000269|PubMed:17062573, ECO:0000269|PubMed:20559320}. |
Subcellular Location | Nucleus. Cytoplasm. Note=Translocates to the nucleus on heterodimerization with E2F family members. |
Tissue Specificity | Predominantly expressed in testis. Low level of expression in pancreas. Highly expressed in ovarian and colon cancer cell lines. {ECO:0000269|PubMed:12097419, ECO:0000269|PubMed:16418725}. |
DP-3 CRISPR/Cas9 KO Plasmid (h) - sc-408089 from Santa Cruz Biotechnology
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DP-3 HDR Plasmid (h) - sc-408089-HDR from Santa Cruz Biotechnology
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DP-3 Double Nickase Plasmid (h) - sc-408089-NIC from Santa Cruz Biotechnology
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DP-3 Double Nickase Plasmid (h2) - sc-408089-NIC-2 from Santa Cruz Biotechnology
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DP-3 CRISPR Activation Plasmid (h) - sc-408089-ACT from Santa Cruz Biotechnology
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DP-3 CRISPR Activation Plasmid (h2) - sc-408089-ACT-2 from Santa Cruz Biotechnology
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DP-3 Lentiviral Activation Particles (h) - sc-408089-LAC from Santa Cruz Biotechnology
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DP-3 Lentiviral Activation Particles (h2) - sc-408089-LAC-2 from Santa Cruz Biotechnology
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DP-3 siRNA (h) - sc-106735 from Santa Cruz Biotechnology
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DP-3 shRNA Plasmid (h) - sc-106735-SH from Santa Cruz Biotechnology
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DP-3 shRNA (h) Lentiviral Particles - sc-106735-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU148611 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN21256 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21256 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR03144 from Sigma-Aldrich
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TFDP3 siRNA (Human) - CRH9650 from Cohesion Biosciences
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TFDP3 RNAi - H00051270-R01 from Novus Biologicals
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TFDP3 - MBS8200408 from MyBioSource
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shRNA set against Human TFDP3 (NM_016521.2) - SHH426188 from Creative biogene
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Human TFDP3 siRNA - orb270152 from Biorbyt
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TFDP3 shRNA Plasmid (Human) - CHH9650 from Cohesion Biosciences
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TFDP3 miRNA 3'UTR clone - MiUTR1H-10341 from Creative biogene
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