CCL5

Gene Symbol CCL5
Entrez Gene 6352
Alt Symbol D17S136E, RANTES, SCYA5, SIS-delta, SISd, TCP228, eoCP
Species Human
Gene Type protein-coding
Description chemokine (C-C motif) ligand 5
Other Description C-C motif chemokine 5|T-cell specific protein p288|beta-chemokine RANTES|eosinophil chemotactic cytokine|regulated upon activation, normally T-expressed, and presumably secreted|small inducible cytokine subfamily A (Cys-Cys), member 5
Swissprots Q4ZGJ1 Q9UBG2 O43646 Q9UC99 P13501 Q9NYA2 Q0QVW8
Accessions AAC63331 AAD14942 AAY22177 ACW84342 BAA76937 BAA76938 BAA76939 CAY55955 EAW80120 P13501 AA443491 AA486131 AF043341 AAC03541 AF266753 AAF73070 AK312212 BAG35145 AW769950 BC008600 AAH08600 BG272739 CB111656 CD695497 CR980938 DQ230537 ABB69929 DQ891490 ABM82416 DQ894681 ABM85607 GD136908 HY265548 M21121 AAA36725 NM_001278736 NP_001265665 NM_002985 NP_002976
Function Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. May activate several chemokine receptors including CCR1, CCR3, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant RANTES protein induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form RANTES(3-68) acts as a natural chemotaxis inhibitor and is a more potent inhibitor of HIV-1- infection. The second processed form RANTES(4-68) exhibits reduced chemotactic and HIV-suppressive activity compared with RANTES(1- 68) and RANTES(3-68) and is generated by an unidentified enzyme associated with monocytes and neutrophils (PubMed:16791620, PubMed:1380064, PubMed:8525373, PubMed:9516414, PubMed:15923218). May also be an agonist of the G protein-coupled receptor GPR75, stimulating inositol trisphosphate production and calcium mobiliz
Subcellular Location Secreted.
Tissue Specificity T-cell and macrophage specific.
Top Pathways TNF signaling pathway, Cytokine-cytokine receptor interaction, Herpes simplex infection, Influenza A, Rheumatoid arthritis

RANTES (R40) Antibody - 2987 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from differentiated THP-1 cells, untreated or treated overnight with LPS, using RANTES (R40) Antibody.

RANTES (P20) Antibody - 2988 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from differentiated THP-1 cells, untreated or treated overnight with LPS, using RANTES (P20) Antibody.

RANTES Antibody (Rodent Specific) - 2989 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of HeLa cells, mock transfected or transfected with mouse RANTES, using RANTES Antibody (Rodent Specific).

RANTES (C-12) - sc-373984 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
RANTES (C-12): sc-373984. Western blot analysis of human recombinant RANTES fusion protein.

RANTES (E-2) - sc-373983 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
RANTES (E-2): sc-373983. Western blot analysis of human recombinant RANTES fusion protein.

RANTES (F-11) - sc-514019 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
RANTES (F-11): sc-514019. Western blot analysis of RANTES expression in human platelet extract.

RANTES (5) - sc-101501 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
RANTES (5): sc-101501. Western blot analysis of human recombinant RANTES.

RANTES (A-4) - sc-365826 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
RANTES (A-4): sc-365826. Western blot analysis of human recombinant RANTES fusion protein.

RANTES (K-15) - sc-34842 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

RANTES (E-14) - sc-34840 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
RANTES (E-14): sc-34840. Western blot analysis of human recombinant RANTES fusion protein.

RANTES (N-14) - sc-34843 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

RANTES (VL2) - sc-32250 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Western blot analysis of human recombinant RANTES fusion protein immunoprecipitated with RANTES (VL2): sc-32250 and detected with RANTES (C-19): sc-1410.

RANTES (VL1) - sc-32246 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
RANTES (VL1): sc-32246. Western blot analysis of human recombinant RANTES.

RANTES (H-50) - sc-20731 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

RANTES (C-19) - sc-1410 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
RANTES (C-19): sc-1410. Western blot analysis of human recombinant RANTES.

Anti-RANTES antibody - ab9679 from Abcam

Prices $392.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ab9679 staining RANTES in Human skeletal muscle (gastrocnemius) tissue sections by Immunohistochemistry (IHC-P - paraformaldehyde-fixed, paraffin-embedded sections). Tissue was fixed with methacarn and blocked with 10% serum for 20 minutes at 25°C; antigen retrieval was by heat mediation in citrate buffer (pH 6) and tris buffer (pH 8). Samples were incubated with primary antibody (2μg/ml) for 1 hour at 25°C. An undiluted HRP-conjugated Mouse anti-rabbit IgG polyclonal was used as the secondary antibody.See Abreview

Anti-RANTES antibody - ab10590 from Abcam

Prices $387.00
Sizes 25 µg
Host Goat
Clonality Polyclonal
ab10590 staining RANTES in human endothelial cells by Immunocytochemistry/ Immunofluorescence.Cells were fixed in paraformaldehyde, permeabilized using Triton, blocked with 1% BSA for 1 hour at 25°C and then incubated with ab10590 at 2µg/ml for 1 hour at 25°C. The secondary used was an FITC conjugated goat anti-rabbit polyclonal used at a 1/100 dilution. Counter stained with TO-PRO3.See Abreview

Anti-RANTES antibody - ab10393 from Abcam

Prices $370.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-RANTES antibody - ab167100 from Abcam

Prices $0.00
Sizes 500 µl
Host Sheep
Clonality Polyclonal

Anti-RANTES antibody [53405.111] - ab10394 from Abcam

Prices $370.00
Sizes 100 µg
Host Rat
Clonality Monoclonal
Clone 53405.111

Anti-RANTES antibody (Biotin) - ab186712 from Abcam

Prices $370.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-RANTES antibody [EPR1359] - ab108933 from Abcam

Prices $379.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR1359
Anti-RANTES antibody [EPR1359] (ab108933) at 1/50000 dilution + RANTES recombinant protein at 0.01 µg

Anti-RANTES antibody [VL-1] - ab9666 from Abcam

Prices $372.00
Sizes 500 µg
Host Mouse
Clonality Monoclonal
Clone VL-1

Anti-RANTES antibody [VL1] - ab52562 from Abcam

Prices $373.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone VL1

Anti-CCL5 / RANTES Antibody - LS-C9918 from LifeSpan Bioscience

Prices $575.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
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