| Gene Symbol |
TMEM115
|
| Entrez Gene |
11070
|
| Alt Symbol |
PL6
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
transmembrane protein 115
|
| Other Description |
PP6|placental protein 6
|
| Swissprots |
Q6IAY4 O14568 A2IDB7 Q9UIX3 Q12893
|
| Accessions |
AAB67308 EAW65115 EAW65116 EAW65117 Q12893 AK314166 BAG36850 BC011948 AAH11948 BC017367 AAH17367 BF305563 CR457020 CAG33301 DQ892106 ABM83032 DQ895300 ABM86226 U09584 AAA92281 NM_007024 NP_008955
|
| Function |
May play a role in retrograde transport of proteins from the Golgi to the endoplasmic reticulum. May indirectly play a role in protein glycosylation in the Golgi. {ECO:0000269|PubMed:24806965}.
|
| Subcellular Location |
Golgi apparatus, Golgi stack membrane {ECO:0000269|PubMed:17973242, ECO:0000269|PubMed:24806965}; Multi- pass membrane protein {ECO:0000303|PubMed:24806965}.
|
| Tissue Specificity |
Expressed strongly in kidney and skeletal muscle, followed by liver, placenta, pancreas, and lung, with low amounts in heart and only traces in brain (PubMed:11085536). Widely expressed with ubiquitous expression in epithelial tissues (at protein level) (PubMed:17973242). {ECO:0000269|PubMed:11085536, ECO:0000269|PubMed:17973242}.
|