Gene Symbol | TMEM115 |
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Entrez Gene | 11070 |
Alt Symbol | PL6 |
Species | Human |
Gene Type | protein-coding |
Description | transmembrane protein 115 |
Other Description | PP6|placental protein 6 |
Swissprots | Q6IAY4 O14568 A2IDB7 Q9UIX3 Q12893 |
Accessions | AAB67308 EAW65115 EAW65116 EAW65117 Q12893 AK314166 BAG36850 BC011948 AAH11948 BC017367 AAH17367 BF305563 CR457020 CAG33301 DQ892106 ABM83032 DQ895300 ABM86226 U09584 AAA92281 NM_007024 NP_008955 |
Function | May play a role in retrograde transport of proteins from the Golgi to the endoplasmic reticulum. May indirectly play a role in protein glycosylation in the Golgi. {ECO:0000269|PubMed:24806965}. |
Subcellular Location | Golgi apparatus, Golgi stack membrane {ECO:0000269|PubMed:17973242, ECO:0000269|PubMed:24806965}; Multi- pass membrane protein {ECO:0000303|PubMed:24806965}. |
Tissue Specificity | Expressed strongly in kidney and skeletal muscle, followed by liver, placenta, pancreas, and lung, with low amounts in heart and only traces in brain (PubMed:11085536). Widely expressed with ubiquitous expression in epithelial tissues (at protein level) (PubMed:17973242). {ECO:0000269|PubMed:11085536, ECO:0000269|PubMed:17973242}. |
PL6 CRISPR/Cas9 KO Plasmid (h) - sc-409808 from Santa Cruz Biotechnology
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PL6 HDR Plasmid (h) - sc-409808-HDR from Santa Cruz Biotechnology
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PL6 Double Nickase Plasmid (h) - sc-409808-NIC from Santa Cruz Biotechnology
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PL6 Double Nickase Plasmid (h2) - sc-409808-NIC-2 from Santa Cruz Biotechnology
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PL6 CRISPR Activation Plasmid (h) - sc-409808-ACT from Santa Cruz Biotechnology
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PL6 CRISPR Activation Plasmid (h2) - sc-409808-ACT-2 from Santa Cruz Biotechnology
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PL6 Lentiviral Activation Particles (h) - sc-409808-LAC from Santa Cruz Biotechnology
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PL6 Lentiviral Activation Particles (h2) - sc-409808-LAC-2 from Santa Cruz Biotechnology
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PL6 siRNA (h) - sc-78005 from Santa Cruz Biotechnology
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PL6 shRNA Plasmid (h) - sc-78005-SH from Santa Cruz Biotechnology
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PL6 shRNA (h) Lentiviral Particles - sc-78005-V from Santa Cruz Biotechnology
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TMEM115 RNAi - H00011070-R01 from Novus Biologicals
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MISSION® esiRNA - EHU014241 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN21480 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21480 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR05611 from Sigma-Aldrich
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TMEM115 siRNA (Human) - CRH7568 from Cohesion Biosciences
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TMEM115 - MBS8236633 from MyBioSource
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shRNA set against Human TMEM115 (NM_007024.4) - SHH428844 from Creative biogene
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shRNA set against Human TMEM115(NM_007024.4) - SHL076282 from Creative biogene
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Human TMEM115 siRNA - orb268070 from Biorbyt
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TMEM115 shRNA Plasmid (Human) - CHH7568 from Cohesion Biosciences
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TMEM115 miRNA 3'UTR clone - MiUTR1H-10482 from Creative biogene
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