Gene Symbol | FCRL5 |
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Entrez Gene | 83416 |
Alt Symbol | BXMAS1, CD307, CD307e, FCRH5, IRTA2, PRO820 |
Species | Human |
Gene Type | protein-coding |
Description | Fc receptor-like 5 |
Other Description | Fc receptor-like protein 5|fc receptor homolog 5|fcR-like protein 5|immune receptor translocation-associated protein 2|immunoglobulin superfamily receptor translocation associated 2 (IRTA2) |
Swissprots | Q495Q2 B7WP94 Q96RD9 Q495Q4 B7WNT9 Q6UY46 Q5VYK9 A0N0M2 |
Accessions | ABK41913 EAW52884 EAW52885 EAW52886 Q96RD9 AF343662 AAK31325 AF343663 AAK31326 AF343664 AAK31327 AF343665 AAK31328 AF369794 AAK50059 AF397453 AAK93971 AK090423 BAC03404 AK090475 BAC03456 AK300010 BAH13192 AK301356 BAG62901 AL832301 AL834187 CAH56486 AY358085 AAQ88452 BC101066 AAI01067 BC101067 AAI01068 BC101068 BC101069 AAI01070 BE676280 XM_011510030 XP_011508332 XM_011510031 XP_011508333 XM_011510032 XP_011508334 XM_011510033 XP_011508335 NM_001195388 NP_001182317 NM_031281 NP_112571 |
Function | May be involved in B-cell development and differentiation in peripheral lymphoid organs and may be useful markers of B-cell stages. May have an immunoregulatory role in marginal zone B-cells. {ECO:0000269|PubMed:11453668}. |
Subcellular Location | Cell membrane {ECO:0000269|PubMed:16849395}; Single-pass type I membrane protein {ECO:0000269|PubMed:16849395}. |
Tissue Specificity | Expressed in marginal zone B-cells, immunoblasts, tonsillar germinal center centrocytes and in the intraepithelial and interfollicular regions of the tonsil. Expressed in many lymphoma cell lines and on hairy cell leukemia cells. Isoform 1, isoform 3, isoform 4 and isoform 5 are detected in lymph node, spleen, bone marrow, and small intestine with preponderance of isoform 3. Expressed in mature and memory B-cells and down-regulated in germinal center cells (at protein level). {ECO:0000269|PubMed:11290337, ECO:0000269|PubMed:11929751, ECO:0000269|PubMed:16849395}. |
Human IRTA2 full length protein - ab164386 from Abcam
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Human IRTA2 protein fragment - ab164387 from Abcam
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FCRL5 / CD307 Antibody Blocking Peptide - LS-E4098 from LifeSpan Bioscience
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FCRL5 / CD307 Antibody Blocking Peptide - LS-E22268 from LifeSpan Bioscience
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Recombinant Human FCRL5/FcRH5/IRTA2 Protein - H00083416-P01 from Novus Biologicals
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Recombinant Human FCRL5/FcRH5/IRTA2 Protein - H00083416-Q01 from Novus Biologicals
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FCRL5/FcRH5/IRTA2 Recombinant Protein - H00083416-G01 from Novus Biologicals
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FCRL5-Antibody-Center-Blocking-Peptide - BP16338c from Abgent, a WuXi AppTec company
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Recombinant Human FCRL5/FcRH5, CF - 2078-FC-050 from R&D Systems
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CD307 / FCRL5 - H00083416-G01 from Acris Antibodies
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CD307 / FCRL5 - H00083416-P01 from Acris Antibodies
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CD307 / FCRL5 - H00083416-Q01-10 from Acris Antibodies
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CD307 / FCRL5 - H00083416-Q01-25 from Acris Antibodies
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FCRL5 fusion protein - ag15716 from Proteintech Group
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Recombinant Human Fc Receptor-Like 5, His-tagged - FCRL5-506H from Creative Biomart
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Recombinant Human FCRL5, His-tagged - FCRL5-12831H from Creative Biomart
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Recombinant Human FCRL5, His-tagged - FCRL5-379H from Creative Biomart
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CD307e Blocking Peptide - CBP3937 from Cohesion Biosciences
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CD307 (Y319) Peptide - BS9214P from Bioworld Technology
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Recombinant Human Fc receptor-like protein 5(FCRL5) ,partial - CSB-YP853494HU CSB-EP853494HU CSB-BP853494HU CSB-MP853494HU from Cusabio
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Recombinant Human FCRL5/FcRH5 Protein, CF - 2078-FC from R&D Systems
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CD307e Blocking Peptide - abx162430 from Abbexa
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FCRL5 fusion protein - Ag24351 from Proteintech Group
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FCRL5 Peptide, Human - M34GP05654H from Creative Peptides
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Fc receptor-like protein 5 (FCRL5), partial, Recombinant Protein - MBS1486087 from MyBioSource
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