Gene Symbol |
RASD2
|
Entrez Gene |
23551
|
Alt Symbol |
MGC:4834, Rhes, TEM2
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
RASD family, member 2
|
Other Description |
GTP-binding protein Rhes|Ras homolog enriched in striatum|tumor endothelial marker 2
|
Swissprots |
Q5THY8 Q96D21 O95520
|
Accessions |
EAW60064 Q96D21 AF279143 AAG00868 AL831936 BC013419 AAH13419 CR456477 CAG30363 CU013027 CAK54458 CU013315 CAK54757 DQ892746 ABM83672 DQ895992 ABM86960 XM_005261442 XP_005261499 XM_011530040 XP_011528342 NM_014310 NP_055125
|
Function |
GTPase signaling protein that binds to and hydrolyzes GTP. Regulates signaling pathways involving G-proteins-coupled receptor and heterotrimeric proteins such as GNB1, GNB2 and GNB3. May be involved in selected striatal competencies, mainly locomotor activity and motor coordination. {ECO:0000269|PubMed:11976265, ECO:0000269|PubMed:19255495}.
|
Subcellular Location |
Cell membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}.
|
Tissue Specificity |
Pancreatic endocrine cells (islets of Langerhans). {ECO:0000269|PubMed:11976265}.
|