Gene Symbol | RASD2 |
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Entrez Gene | 23551 |
Alt Symbol | MGC:4834, Rhes, TEM2 |
Species | Human |
Gene Type | protein-coding |
Description | RASD family, member 2 |
Other Description | GTP-binding protein Rhes|Ras homolog enriched in striatum|tumor endothelial marker 2 |
Swissprots | Q5THY8 Q96D21 O95520 |
Accessions | EAW60064 Q96D21 AF279143 AAG00868 AL831936 BC013419 AAH13419 CR456477 CAG30363 CU013027 CAK54458 CU013315 CAK54757 DQ892746 ABM83672 DQ895992 ABM86960 XM_005261442 XP_005261499 XM_011530040 XP_011528342 NM_014310 NP_055125 |
Function | GTPase signaling protein that binds to and hydrolyzes GTP. Regulates signaling pathways involving G-proteins-coupled receptor and heterotrimeric proteins such as GNB1, GNB2 and GNB3. May be involved in selected striatal competencies, mainly locomotor activity and motor coordination. {ECO:0000269|PubMed:11976265, ECO:0000269|PubMed:19255495}. |
Subcellular Location | Cell membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}. |
Tissue Specificity | Pancreatic endocrine cells (islets of Langerhans). {ECO:0000269|PubMed:11976265}. |
Dexras2 CRISPR/Cas9 KO Plasmid (h) - sc-406131 from Santa Cruz Biotechnology
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Dexras2 HDR Plasmid (h) - sc-406131-HDR from Santa Cruz Biotechnology
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Dexras2 Double Nickase Plasmid (h) - sc-406131-NIC from Santa Cruz Biotechnology
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Dexras2 Double Nickase Plasmid (h2) - sc-406131-NIC-2 from Santa Cruz Biotechnology
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Dexras2 CRISPR Activation Plasmid (h) - sc-406131-ACT from Santa Cruz Biotechnology
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Dexras2 CRISPR Activation Plasmid (h2) - sc-406131-ACT-2 from Santa Cruz Biotechnology
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Dexras2 Lentiviral Activation Particles (h) - sc-406131-LAC from Santa Cruz Biotechnology
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Dexras2 Lentiviral Activation Particles (h2) - sc-406131-LAC-2 from Santa Cruz Biotechnology
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Dexras2 siRNA (h) - sc-105290 from Santa Cruz Biotechnology
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Dexras2 shRNA Plasmid (h) - sc-105290-SH from Santa Cruz Biotechnology
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Dexras2 shRNA (h) Lentiviral Particles - sc-105290-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN17977 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17977 from Sigma-Aldrich
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RASD2 siRNA (Human) - CRH8353 from Cohesion Biosciences
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RASD2 - MBS8234336 from MyBioSource
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shRNA set against Human RASD2 (NM_014310.3) - SHH389944 from Creative biogene
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shRNA set against Human RASD2(NM_014310.3) - SHR166033 from Creative biogene
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Human RASD2 siRNA - orb268855 from Biorbyt
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RASD2 shRNA Plasmid (Human) - CHH8353 from Cohesion Biosciences
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RASD2 miRNA 3'UTR clone - MiUTR1H-08641 from Creative biogene
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