| Gene Symbol |
KLHL9
|
| Entrez Gene |
55958
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
kelch-like family member 9
|
| Other Description |
kelch-like 9|kelch-like protein 9
|
| Swissprots |
Q9P2J3 Q8TCQ2
|
| Accessions |
EAW58614 Q9P2J3 AB037775 BAA92592 AK022805 AK023630 BAB14623 AK025468 AK091715 BAG52403 AL713669 CAD28475 AY172949 AAO39718 BC039133 AAH39133 BC052776 BC064958 BC105008 AAI05009 BC113513 AAI13514 BX538121 CAD98027 DR978657 NM_001040713 NM_018847 NP_061335
|
| Function |
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for mitotic progression and cytokinesis. The BCR(KLHL9-KLHL13) E3 ubiquitin ligase complex mediates the ubiquitination of AURKB and controls the dynamic behavior of AURKB on mitotic chromosomes and thereby coordinates faithful mitotic progression and completion of cytokinesis. {ECO:0000269|PubMed:14528312, ECO:0000269|PubMed:17543862, ECO:0000269|PubMed:19995937}.
|
| Top Pathways |
Ubiquitin mediated proteolysis
|