Gene Symbol | KLHL9 |
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Entrez Gene | 55958 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | kelch-like family member 9 |
Other Description | kelch-like 9|kelch-like protein 9 |
Swissprots | Q9P2J3 Q8TCQ2 |
Accessions | EAW58614 Q9P2J3 AB037775 BAA92592 AK022805 AK023630 BAB14623 AK025468 AK091715 BAG52403 AL713669 CAD28475 AY172949 AAO39718 BC039133 AAH39133 BC052776 BC064958 BC105008 AAI05009 BC113513 AAI13514 BX538121 CAD98027 DR978657 NM_001040713 NM_018847 NP_061335 |
Function | Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for mitotic progression and cytokinesis. The BCR(KLHL9-KLHL13) E3 ubiquitin ligase complex mediates the ubiquitination of AURKB and controls the dynamic behavior of AURKB on mitotic chromosomes and thereby coordinates faithful mitotic progression and completion of cytokinesis. {ECO:0000269|PubMed:14528312, ECO:0000269|PubMed:17543862, ECO:0000269|PubMed:19995937}. |
Top Pathways | Ubiquitin mediated proteolysis |
KLHL9 CRISPR/Cas9 KO Plasmid (h) - sc-406655 from Santa Cruz Biotechnology
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KLHL9 HDR Plasmid (h) - sc-406655-HDR from Santa Cruz Biotechnology
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KLHL9 Double Nickase Plasmid (h) - sc-406655-NIC from Santa Cruz Biotechnology
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KLHL9 Double Nickase Plasmid (h2) - sc-406655-NIC-2 from Santa Cruz Biotechnology
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KLHL9 CRISPR Activation Plasmid (h) - sc-406655-ACT from Santa Cruz Biotechnology
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KLHL9 CRISPR Activation Plasmid (h2) - sc-406655-ACT-2 from Santa Cruz Biotechnology
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KLHL9 Lentiviral Activation Particles (h) - sc-406655-LAC from Santa Cruz Biotechnology
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KLHL9 Lentiviral Activation Particles (h2) - sc-406655-LAC-2 from Santa Cruz Biotechnology
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KLHL9 siRNA (h) - sc-92573 from Santa Cruz Biotechnology
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KLHL9 shRNA Plasmid (h) - sc-92573-SH from Santa Cruz Biotechnology
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KLHL9 shRNA (h) Lentiviral Particles - sc-92573-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU140141 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN11302 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND11302 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR13218 from Sigma-Aldrich
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KLHL9 siRNA (Human) - CRJ1022 from Cohesion Biosciences
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shRNA set against Human KLHL9 (NM_018847.2) - SHH326419 from Creative biogene
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shRNA set against Human KLHL9(NM_018847.2) - SHL201924 from Creative biogene
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Human KLHL9 siRNA - orb271523 from Biorbyt
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KLHL9 shRNA Plasmid (Human) - CHJ1022 from Cohesion Biosciences
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KLHL9 miRNA 3'UTR clone - MiUTR1H-05383 from Creative biogene
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