| Gene Symbol |
DYX1C1
|
| Entrez Gene |
161582
|
| Alt Symbol |
CILD25, DNAAF4, DYX1, DYXC1, EKN1, RD
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
dyslexia susceptibility 1 candidate 1
|
| Other Description |
dynein, axonemal, assembly factor 4|dyslexia susceptibility 1 candidate gene 1 protein
|
| Swissprots |
Q8N1S6 Q8WXU2 Q6P5Y9
|
| Accessions |
EAW77490 EAW77491 Q8WXU2 AF337549 AAL73230 AK095201 BAC04498 AK302316 BAG63654 BC017392 BC062564 AAH62564 BM971229 NM_001033559 NP_001028731 NM_001033560 NP_001028732 NM_130810 NP_570722
|
| Function |
Involved in neuronal migration during development of the cerebral neocortex. May regulate the stability and proteasomal degradation of the estrogen receptors that play an important role in neuronal differentiation, survival and plasticity. Axonemal dynein assembly factor required for ciliary motility. {ECO:0000269|PubMed:19423554, ECO:0000269|PubMed:23872636}.
|
| Subcellular Location |
Nucleus. Cytoplasm.
|
| Tissue Specificity |
Expressed in several tissues, including brain, lung, kidney and testis. In brain localizes to a fraction of cortical neurons and white matter glial cells. {ECO:0000269|PubMed:12954984}.
|