MFNG

Gene Symbol MFNG
Entrez Gene 4242
Alt Symbol -
Species Human
Gene Type protein-coding
Description MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
Other Description O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase|beta-1,3-N-acetylglucosaminyltransferase manic fringe
Swissprots Q504S9 O00587 O43730 B4DLT6
Accessions CAB07511 CAP58790 CAP58791 CAP58792 CAP58793 EAW60161 EAW60162 O00587 AI363008 AK292123 BAF84812 AK297149 BAG59648 AK297833 BAG60167 AK316555 BAG65633 BC094814 AAH94814 BM457814 CR456518 CAG30404 CU013118 CAK54549 CU013406 CAK54848 DA815501 U94352 AAC51358 NM_001166343 NP_001159815 NM_002405 NP_002396 NR_029413
Function Glycosyltransferase involved in the elongation of O- linked ligands to activate Notch signaling. Possesses fucose- specific beta-1,3-N-acetylglucosaminyltransferase activity. {ECO:0000269|PubMed:10935626}.
Subcellular Location Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
Top Pathways Other types of O-glycan biosynthesis, Notch signaling pathway