| Gene Symbol |
MFNG
|
| Entrez Gene |
4242
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
|
| Other Description |
O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase|beta-1,3-N-acetylglucosaminyltransferase manic fringe
|
| Swissprots |
Q504S9 O00587 O43730 B4DLT6
|
| Accessions |
CAB07511 CAP58790 CAP58791 CAP58792 CAP58793 EAW60161 EAW60162 O00587 AI363008 AK292123 BAF84812 AK297149 BAG59648 AK297833 BAG60167 AK316555 BAG65633 BC094814 AAH94814 BM457814 CR456518 CAG30404 CU013118 CAK54549 CU013406 CAK54848 DA815501 U94352 AAC51358 NM_001166343 NP_001159815 NM_002405 NP_002396 NR_029413
|
| Function |
Glycosyltransferase involved in the elongation of O- linked ligands to activate Notch signaling. Possesses fucose- specific beta-1,3-N-acetylglucosaminyltransferase activity. {ECO:0000269|PubMed:10935626}.
|
| Subcellular Location |
Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
|
| Top Pathways |
Other types of O-glycan biosynthesis, Notch signaling pathway
|
![Western Blot: Manic Fringe Overexpression Lysate (Adult Normal) [NBL1-13041] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Manic Fringe.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/8953_Manic%2520Fringe%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-13041-img0002.jpg)