Gene Symbol | PLSCR2 |
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Entrez Gene | 57047 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | phospholipid scramblase 2 |
Other Description | PL scramblase 2|ca(2+)-dependent phospholipid scramblase 2 |
Swissprots | J3KR76 Q6NSW9 Q9NRY7 B4DXC3 Q7Z4L7 Q0VAQ1 |
Accessions | CBH19416 CBH30688 EAW78931 EAW78932 Q9NRY7 AA813518 AF159441 AAF91082 AK301909 BAG63335 BC055415 AAH55415 BC069785 AAH69785 BC120969 AAI20970 BC141969 AAI41970 BU852276 XM_011513012 XP_011511314 XM_011513013 XP_011511315 XM_011513014 XP_011511316 XM_011513015 XP_011511317 XM_011513016 XP_011511318 XM_011513017 XP_011511319 XM_011513018 XP_011511320 XM_011513019 XP_011511321 XM_011513020 XP_011511322 XM_011513021 XP_011511323 XM_011513022 XP_011511324 XM_011513023 XP_011511325 XM_011513024 XP_011511326 XM_011513025 XP_011511327 XM_011513026 XP_011511328 XM_011513027 XP_011511329 XM_011513028 XP_011511330 XM_011513029 XP_011511331 XM_011513030 XP_011511332 NM_001199978 NP_001186907 NM_001199979 NP_001186908 NM_020359 NP_065092 |
Function | May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system. |
Subcellular Location | Membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. |
Tissue Specificity | Expression of isoform 1 seems restricted to testis. {ECO:0000269|PubMed:10930526}. |
PLSCR2 CRISPR/Cas9 KO Plasmid (h) - sc-416663 from Santa Cruz Biotechnology
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PLSCR2 HDR Plasmid (h) - sc-416663-HDR from Santa Cruz Biotechnology
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PLSCR2 Double Nickase Plasmid (h) - sc-416663-NIC from Santa Cruz Biotechnology
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PLSCR2 Double Nickase Plasmid (h2) - sc-416663-NIC-2 from Santa Cruz Biotechnology
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PLSCR2 CRISPR Activation Plasmid (h) - sc-416663-ACT from Santa Cruz Biotechnology
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PLSCR2 CRISPR Activation Plasmid (h2) - sc-416663-ACT-2 from Santa Cruz Biotechnology
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PLSCR2 Lentiviral Activation Particles (h) - sc-416663-LAC from Santa Cruz Biotechnology
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PLSCR2 Lentiviral Activation Particles (h2) - sc-416663-LAC-2 from Santa Cruz Biotechnology
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PLSCR2 siRNA (h) - sc-77986 from Santa Cruz Biotechnology
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PLSCR2 shRNA Plasmid (h) - sc-77986-SH from Santa Cruz Biotechnology
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PLSCR2 shRNA (h) Lentiviral Particles - sc-77986-V from Santa Cruz Biotechnology
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PLSCR2 RNAi - H00057047-R01 from Novus Biologicals
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MISSION® esiRNA - EHU114591 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR01145 from Sigma-Aldrich
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PLSCR2 siRNA (Human) - CRJ1299 from Cohesion Biosciences
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Human PLSCR2 siRNA - orb271800 from Biorbyt
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PLSCR2 shRNA Plasmid (Human) - CHJ1299 from Cohesion Biosciences
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