Gene Symbol | H1FOO |
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Entrez Gene | 132243 |
Alt Symbol | H1.8, osH1 |
Species | Human |
Gene Type | protein-coding |
Description | H1 histone family, member O, oocyte-specific |
Other Description | histone H1oo|oocyte-specific histone H1|oocyte-specific linker histone H1 |
Swissprots | Q86WT7 Q8IZA3 |
Accessions | EAW79242 EAW79243 Q8IZA3 AY158091 AAN46899 BC047943 AAH47943 BM564157 XM_005247123 XP_005247180 NM_001308262 NP_001295191 NM_153833 NP_722575 |
Function | May play a key role in the control of gene expression during oogenesis and early embryogenesis, presumably through the perturbation of chromatin structure. Essential for meiotic maturation of germinal vesicle-stage oocytes. The somatic type linker histone H1c is rapidly replaced by H1oo in a donor nucleus transplanted into an oocyte. The greater mobility of H1oo as compared to H1c may contribute to this rapid replacement and increased instability of the embryonic chromatin structure. The rapid replacement of H1c with H1oo may play an important role in nuclear remodeling (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000250}. Nucleus {ECO:0000255|PROSITE-ProRule:PRU00837}. Chromosome {ECO:0000255|PROSITE-ProRule:PRU00837}. |
Tissue Specificity | Oocyte-specific. {ECO:0000269|PubMed:12711322}. |
Histone H1oo peptide - ab194535 from Abcam
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Human Histone H1 full length protein - ab198676 from Abcam
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Human Histone H1 peptide - ab17588 from Abcam
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Human Histone H1 peptide - ab30741 from Abcam
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Human Histone H1 peptide - ab35888 from Abcam
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Human Histone H1 peptide - ab35920 from Abcam
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Human Histone H1 peptide - ab36686 from Abcam
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Human Histone H1oo full length protein - ab165363 from Abcam
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H1FOO Antibody Blocking Peptide - LS-E4803 from LifeSpan Bioscience
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H1FOO Antibody Blocking Peptide - LS-E19200 from LifeSpan Bioscience
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H1FOO Antibody Blocking Peptide - LS-E19201 from LifeSpan Bioscience
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Recombinant Human H1FOO Protein - H00132243-P01 from Novus Biologicals
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H1FOO-Antibody-Center-Blocking-Peptide - BP17183c from Abgent, a WuXi AppTec company
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H1FOO Blocking Peptide - 33R-4254 from Fitzgerald
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H1FOO Blocking Peptide - 33R-5709 from Fitzgerald
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Histone H1oo / H1FOO - H00132243-P01-10 from Acris Antibodies
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Histone H1oo / H1FOO - H00132243-P01-25 from Acris Antibodies
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Histone H1oo (P18) Peptide - BS1656P from Bioworld Technology
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Histone H1oo peptide - pep0371 from Covalab
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Recombinant Human Histone H1oo(H1FOO) - CSB-YP809025HU CSB-EP809025HU CSB-BP809025HU CSB-MP809025HU from Cusabio
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Histone H1 protein - ab89813 from Abcam
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Histone H1oo / H1FOO - TP315554 from Acris Antibodies
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H1FOO Recombinant Protein Antigen - NBP1-86265PEP from Novus Biologicals
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H1FOO Peptide, Human - M34GP06801H from Creative Peptides
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Histone H1oo (H1FOO), Recombinant Protein - MBS1455324 from MyBioSource
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