Gene Symbol |
SLC25A12
|
Entrez Gene |
8604
|
Alt Symbol |
AGC1, ARALAR
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
solute carrier family 25 (aspartate/glutamate carrier), member 12
|
Other Description |
araceli hiperlarga|calcium binding mitochondrial carrier superfamily member Aralar1|calcium-binding mitochondrial carrier protein Aralar1|mitochondrial aspartate glutamate carrier 1|solute carrier family 25 (mitochondrial carrier, Aralar), member 12
|
Swissprots |
O75746 Q96AM8 B3KR64
|
Accessions |
AAY24134 EAX11196 EAX11197 O75746 AJ496568 CAD43090 AK022828 BAG51120 AK054941 AK091071 BAG52276 AK294638 BAG57817 BC016932 AAH16932 DN993435 DQ891540 ABM82466 EU176607 ABW03408 Y14494 CAA74834 XM_005246923 XP_005246980 XM_011512069 XP_011510371 XM_011512070 XP_011510372 NM_003705 NP_003696 NR_047549
|
Function |
Catalyzes the calcium-dependent exchange of cytoplasmic glutamate with mitochondrial aspartate across the mitochondrial inner membrane. May have a function in the urea cycle. {ECO:0000269|PubMed:11566871}.
|
Subcellular Location |
Mitochondrion inner membrane {ECO:0000269|PubMed:9722566}; Multi-pass membrane protein {ECO:0000269|PubMed:9722566}.
|
Tissue Specificity |
High levels in heart and skeletal muscle, low in brain and very low in kidney. {ECO:0000269|PubMed:10369257, ECO:0000269|PubMed:9722566}.
|