Gene Symbol | SLC25A12 |
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Entrez Gene | 8604 |
Alt Symbol | AGC1, ARALAR |
Species | Human |
Gene Type | protein-coding |
Description | solute carrier family 25 (aspartate/glutamate carrier), member 12 |
Other Description | araceli hiperlarga|calcium binding mitochondrial carrier superfamily member Aralar1|calcium-binding mitochondrial carrier protein Aralar1|mitochondrial aspartate glutamate carrier 1|solute carrier family 25 (mitochondrial carrier, Aralar), member 12 |
Swissprots | O75746 Q96AM8 B3KR64 |
Accessions | AAY24134 EAX11196 EAX11197 O75746 AJ496568 CAD43090 AK022828 BAG51120 AK054941 AK091071 BAG52276 AK294638 BAG57817 BC016932 AAH16932 DN993435 DQ891540 ABM82466 EU176607 ABW03408 Y14494 CAA74834 XM_005246923 XP_005246980 XM_011512069 XP_011510371 XM_011512070 XP_011510372 NM_003705 NP_003696 NR_047549 |
Function | Catalyzes the calcium-dependent exchange of cytoplasmic glutamate with mitochondrial aspartate across the mitochondrial inner membrane. May have a function in the urea cycle. {ECO:0000269|PubMed:11566871}. |
Subcellular Location | Mitochondrion inner membrane {ECO:0000269|PubMed:9722566}; Multi-pass membrane protein {ECO:0000269|PubMed:9722566}. |
Tissue Specificity | High levels in heart and skeletal muscle, low in brain and very low in kidney. {ECO:0000269|PubMed:10369257, ECO:0000269|PubMed:9722566}. |
ARALAR CRISPR/Cas9 KO Plasmid (h) - sc-403673 from Santa Cruz Biotechnology
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ARALAR HDR Plasmid (h) - sc-403673-HDR from Santa Cruz Biotechnology
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ARALAR Double Nickase Plasmid (h) - sc-403673-NIC from Santa Cruz Biotechnology
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ARALAR Double Nickase Plasmid (h2) - sc-403673-NIC-2 from Santa Cruz Biotechnology
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ARALAR CRISPR Activation Plasmid (h) - sc-403673-ACT from Santa Cruz Biotechnology
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ARALAR CRISPR Activation Plasmid (h2) - sc-403673-ACT-2 from Santa Cruz Biotechnology
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ARALAR Lentiviral Activation Particles (h) - sc-403673-LAC from Santa Cruz Biotechnology
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ARALAR Lentiviral Activation Particles (h2) - sc-403673-LAC-2 from Santa Cruz Biotechnology
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ARALAR siRNA (h) - sc-94426 from Santa Cruz Biotechnology
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ARALAR shRNA Plasmid (h) - sc-94426-SH from Santa Cruz Biotechnology
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ARALAR shRNA (h) Lentiviral Particles - sc-94426-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU011211 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN2172 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2172 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR07965 from Sigma-Aldrich
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SLC25A12 siRNA (Human) - CRH5652 from Cohesion Biosciences
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SLC25A12 RNAi - H00008604-R01 from Novus Biologicals
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SLC25A12 - MBS8231654 from MyBioSource
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shRNA set against Human SLC25A12 (NM_003705.4) - SHH409416 from Creative biogene
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SLC25A12 shRNA Plasmid (Human) - CHH5652 from Cohesion Biosciences
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SLC25A12 miRNA 3'UTR clone - MiUTR3H-06169 from Creative biogene
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