Gene Symbol | PTHLH |
---|---|
Entrez Gene | 286767 |
Alt Symbol | PTHrP |
Species | Bovine |
Gene Type | protein-coding |
Description | parathyroid hormone-like hormone |
Other Description | PTH-rP|parathyroid hormone-related protein |
Swissprots | Q8HYS1 P58073 A6QPN9 |
Accessions | DAA29452 P58073 AB097837 BAC44840 BC149411 AAI49412 XM_005206914 XP_005206971 XM_010805380 XP_010803682 XM_010805381 XP_010803683 NM_174753 NP_777178 |
Function | Neuroendocrine peptide which is a critical regulator of cellular and organ growth, development, migration, differentiation and survival and of epithelial calcium ion transport. Regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. Required for skeletal homeostasis. Promotes mammary mesenchyme differentiation and bud outgrowth by modulating mesenchymal cell responsiveness to BMPs. Upregulates BMPR1A expression in the mammary mesenchyme and this increases the sensitivity of these cells to BMPs and allows them to respond to BMP4 in a paracrine and/or autocrine fashion. BMP4 signaling in the mesenchyme, in turn, triggers epithelial outgrowth and augments MSX2 expression, which causes the mammary mesenchyme to inhibit hair follicle formation within the nipple sheath (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Secreted {ECO:0000250}. |
Tissue Specificity | Expressed in the mammary gland. |
Cow PTHrP ELISA Kit - abx150187 from Abbexa
|
||||||||||
Parathyroid Hormone Related Protein (PTHrP), Bovine, ELISA Kit - SEA819Bo from ARP American Research Products
|
||||||||||
Parathyroid hormone-related protein, PTHLH, Bovine, ELISA Kit - E0819b from ARP American Research Products
|
||||||||||
Bovine PTHRP ELISA Kit - BP0581 from NeoScientific
|
||||||||||
Bovine Parathyroid Hormone Related Protein ELISA - E11P0574 from BlueGene Biotech
|
||||||||||
Parathyroid Hormone Related Protein (PTHrP), Bovine, ELISA Kit - DL-PTHrP-b from ARP American Research Products
|
||||||||||
Cow PTHrP ELISA Kit - abx575014 from Abbexa
|
||||||||||
Bovine PTHLH ELISA Kit - E094854 from Biobool
|
||||||||||
Bovine PTHRP ELISA Kit - EBP0581 from ABclonal
|
||||||||||
PTHLH ELISA Kit (Bovine) (OKCD02831) - OKCD02831 from Aviva Systems Biology
|
||||||||||
Parathyroid Hormone Related Protein (PTHrP), ELISA Kit - MBS455233 from MyBioSource
|
||||||||||
PTHLH ELISA Kit (Bovine) (OKEH07127) - OKEH07127 from Aviva Systems Biology
|