| Gene Symbol |
GSDMA
|
| Entrez Gene |
284110
|
| Alt Symbol |
FKSG9, GSDM, GSDM1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
gasdermin A
|
| Other Description |
gasdermin 1|gasdermin-1|gasdermin-A
|
| Swissprots |
Q8N1M6 Q32MC5 Q96QA5 Q86VE7
|
| Accessions |
EAW60624 Q96QA5 AA826386 AB093591 BAC75636 AF307953 AAL14426 AK096439 BAC04790 BC109197 AAI09198 XM_006721832 XP_006721895 XM_011524651 XP_011522953 NM_178171 NP_835465
|
| Function |
Induces apoptosis. {ECO:0000269|PubMed:17471240}.
|
| Subcellular Location |
Cytoplasm, perinuclear region {ECO:0000269|PubMed:17471240}.
|
| Tissue Specificity |
Expressed predominantly in the gastrointestinal tract and in the skin at a lower level. Also detected in mammary gland. Detected in mucus-secreting pit cells of the gastric epithelium. Not expressed in gastric cancer cells. {ECO:0000269|PubMed:10967128, ECO:0000269|PubMed:17471240}.
|