Gene Symbol | GSDMA |
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Entrez Gene | 284110 |
Alt Symbol | FKSG9, GSDM, GSDM1 |
Species | Human |
Gene Type | protein-coding |
Description | gasdermin A |
Other Description | gasdermin 1|gasdermin-1|gasdermin-A |
Swissprots | Q8N1M6 Q32MC5 Q96QA5 Q86VE7 |
Accessions | EAW60624 Q96QA5 AA826386 AB093591 BAC75636 AF307953 AAL14426 AK096439 BAC04790 BC109197 AAI09198 XM_006721832 XP_006721895 XM_011524651 XP_011522953 NM_178171 NP_835465 |
Function | Induces apoptosis. {ECO:0000269|PubMed:17471240}. |
Subcellular Location | Cytoplasm, perinuclear region {ECO:0000269|PubMed:17471240}. |
Tissue Specificity | Expressed predominantly in the gastrointestinal tract and in the skin at a lower level. Also detected in mammary gland. Detected in mucus-secreting pit cells of the gastric epithelium. Not expressed in gastric cancer cells. {ECO:0000269|PubMed:10967128, ECO:0000269|PubMed:17471240}. |
gasdermin CRISPR/Cas9 KO Plasmid (h) - sc-410658 from Santa Cruz Biotechnology
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gasdermin HDR Plasmid (h) - sc-410658-HDR from Santa Cruz Biotechnology
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gasdermin Double Nickase Plasmid (h) - sc-410658-NIC from Santa Cruz Biotechnology
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gasdermin Double Nickase Plasmid (h2) - sc-410658-NIC-2 from Santa Cruz Biotechnology
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gasdermin CRISPR Activation Plasmid (h) - sc-410658-ACT from Santa Cruz Biotechnology
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gasdermin CRISPR Activation Plasmid (h2) - sc-410658-ACT-2 from Santa Cruz Biotechnology
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gasdermin Lentiviral Activation Particles (h) - sc-410658-LAC from Santa Cruz Biotechnology
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gasdermin Lentiviral Activation Particles (h2) - sc-410658-LAC-2 from Santa Cruz Biotechnology
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gasdermin siRNA (h) - sc-75109 from Santa Cruz Biotechnology
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gasdermin shRNA Plasmid (h) - sc-75109-SH from Santa Cruz Biotechnology
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gasdermin shRNA (h) Lentiviral Particles - sc-75109-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU046351 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN9719 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9719 from Sigma-Aldrich
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GSDMA siRNA (Human) - CRJ6972 from Cohesion Biosciences
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GSDMA - MBS8234380 from MyBioSource
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shRNA set against Human GSDMA (NM_178171.4) - SHH308354 from Creative biogene
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Human GSDMA siRNA - orb277473 from Biorbyt
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GSDMA shRNA Plasmid (Human) - CHJ6972 from Cohesion Biosciences
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GSDMA miRNA 3'UTR clone - MiUTR1H-04304 from Creative biogene
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