| Gene Symbol |
Slc28a3
|
| Entrez Gene |
114304
|
| Alt Symbol |
Cnt3
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
solute carrier family 28 (sodium-coupled nucleoside transporter), member 3
|
| Other Description |
CNT 3|concentrative Na(+)-nucleoside cotransporter 3|concentrative Na+-nucleoside cotransporter|mCNT3|solute carrier family 28 member 3
|
| Swissprots |
Q8BWE2 Q3UM72 Q9ERH8 Q91VD7
|
| Accessions |
EDL41268 Q9ERH8 AF305211 AAG22552 AK052784 BAC35145 AK085680 AK145077 BAE26226 AK164740 AK164752 BC010472 AAH10472 BC013783 AAH13783 BC037061 BY736278 NM_022317 NP_071712
|
| Function |
Sodium-dependent, pyrimidine- and purine-selective. Involved in the homeostasis of endogenous nucleosides. Exhibits the transport characteristics of the nucleoside transport system cib or N3 subtype (N3/cib) (with marked transport of both thymidine and inosine). Employs a 2:1 sodium/nucleoside ratio. Also able to transport gemcitabine, 3'-azido-3'-deoxythymidine (AZT), ribavirin and 3-deazauridine (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
|