Gene Symbol | Slc28a3 |
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Entrez Gene | 114304 |
Alt Symbol | Cnt3 |
Species | Mouse |
Gene Type | protein-coding |
Description | solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 |
Other Description | CNT 3|concentrative Na(+)-nucleoside cotransporter 3|concentrative Na+-nucleoside cotransporter|mCNT3|solute carrier family 28 member 3 |
Swissprots | Q8BWE2 Q3UM72 Q9ERH8 Q91VD7 |
Accessions | EDL41268 Q9ERH8 AF305211 AAG22552 AK052784 BAC35145 AK085680 AK145077 BAE26226 AK164740 AK164752 BC010472 AAH10472 BC013783 AAH13783 BC037061 BY736278 NM_022317 NP_071712 |
Function | Sodium-dependent, pyrimidine- and purine-selective. Involved in the homeostasis of endogenous nucleosides. Exhibits the transport characteristics of the nucleoside transport system cib or N3 subtype (N3/cib) (with marked transport of both thymidine and inosine). Employs a 2:1 sodium/nucleoside ratio. Also able to transport gemcitabine, 3'-azido-3'-deoxythymidine (AZT), ribavirin and 3-deazauridine (By similarity). {ECO:0000250}. |
Subcellular Location | Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. |
CNT3 CRISPR/Cas9 KO Plasmid (m) - sc-431102 from Santa Cruz Biotechnology
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CNT3 HDR Plasmid (m) - sc-431102-HDR from Santa Cruz Biotechnology
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CNT3 Double Nickase Plasmid (m) - sc-431102-NIC from Santa Cruz Biotechnology
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CNT3 Double Nickase Plasmid (m2) - sc-431102-NIC-2 from Santa Cruz Biotechnology
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CNT3 CRISPR Activation Plasmid (m) - sc-431102-ACT from Santa Cruz Biotechnology
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CNT3 CRISPR Activation Plasmid (m2) - sc-431102-ACT-2 from Santa Cruz Biotechnology
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CNT3 Lentiviral Activation Particles (m) - sc-431102-LAC from Santa Cruz Biotechnology
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CNT3 Lentiviral Activation Particles (m2) - sc-431102-LAC-2 from Santa Cruz Biotechnology
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CNT3 siRNA (m) - sc-60426 from Santa Cruz Biotechnology
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CNT3 shRNA Plasmid (m) - sc-60426-SH from Santa Cruz Biotechnology
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CNT3 shRNA (m) Lentiviral Particles - sc-60426-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU043681 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN41402 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND41402 from Sigma-Aldrich
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SLC28A3 siRNA (Mouse) - CRN1183 from Cohesion Biosciences
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SLC28A3 - MBS826931 from MyBioSource
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shRNA set against Mouse SLC28A3 (NM_022317.3) - SHH410140 from Creative biogene
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shRNA set against Mouse Slc28a3(NM_022317.3) - SHL005136 from Creative biogene
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SLC28A3 shRNA Plasmid (Mouse) - CHN1183 from Cohesion Biosciences
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SLC28A3 miRNA 3'UTR clone - MiUTR1M-10835 from Creative biogene
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