CIDEA

Gene Symbol	CIDEA
Entrez Gene	1149
Alt Symbol	CIDE-A
Species	Human
Gene Type	protein-coding
Description	cell death-inducing DFFA-like effector a
Other Description	cell death activator CIDE-A
Swissprots	O60543 Q6UPR7 B0YIY7
Accessions	ACA05965 ACA05966 ADU05471 EAX01555 O60543 AA683375 AF041378 AAC34987 AK122762 BAG53714 AY364639 AAQ65241 BC031896 AAH31896 BQ718688 R73455 XM_011525602 XP_011523904 NM_001279 NP_001270 NR_036468
Function	Acts as a CEBPB coactivator in mammary epithelial cells to control the expression of a subset of CEBPB downstream target genes, including ID2, IGF1, PRLR, SOCS1, SOCS3, XDH, but not casein. By interacting with CEBPB, strengthens the association of CEBPB with the XDH promoter, increases histone acetylation and dissociates HDAC1 from the promoter (By similarity). Binds to lipid droplets and regulates their enlargement, thereby restricting lipolysis and favoring storage. At focal contact sites between lipid droplets, promotes directional net neutral lipid transfer from the smaller to larger lipid droplets. The transfer direction may be driven by the internal pressure difference between the contacting lipid droplet pair and occurs at a lower rate than that promoted by CIDEC. When overexpressed, induces apoptosis. The physiological significance of its role in apoptosis is unclear. {ECO:0000250, ECO:0000269|PubMed:19843876}.
Subcellular Location	Lipid droplet {ECO:0000269|PubMed:18509062}. Nucleus {ECO:0000250}. Note=Enriched at lipid droplet contact sites. Has been shown to localize to mitonchondria, where it could interact with UCP1 and hence inhibit UCP1 uncoupling activity (By similarity). These data could not be confirmed (PubMed:18509062). {ECO:0000250, ECO:0000269|PubMed:18509062}.
Tissue Specificity	Expressed in omental and subcutaneous adipose tissue (at protein level). {ECO:0000269|PubMed:18509062}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

CIDE A peptide - ab8434 from Abcam Category Peptide Prices $181.00 Sizes 50 µg

Human CIDE A full length protein - ab152281 from Abcam Category Protein Source Wheat germ Species Human

CIDEA / CIDE-A Antibody Blocking Peptide - LS-E2932 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CIDEA / CIDE-A Antibody Blocking Peptide - LS-E29882 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

CIDEA / CIDE-A Antibody Blocking Peptide - LS-E29883 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

Recombinant Human CIDEA Protein - H00001149-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

CIDEA Blocking Peptide - NBP1-76951PEP from Novus Biologicals Category Peptide Prices $129.00 Sizes 50 µg Species Human

CIDEA-Antibody-C-term-Blocking-peptide - BP14057b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

CIDE-A - H00001149-P01 from Acris Antibodies Category Protein Prices $340.00 Sizes 2 µg Species Human

CIDE-A Control Peptide - AP30229CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

CIDE-A Peptide - 2085P from ProSci Category Peptide Species Human

CIDE-A Peptide - 2089P from ProSci Category Peptide Species Mouse

CIDEA fusion protein - ag3824 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Cell Death Inducing DFFA Like Effector A (CIDEA) - RPL340Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Cell Death Inducing DFFA Like Effector A (CIDEA) - RPL340Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Human Cell death activator CIDE-A(CIDEA) - CSB-YP005431HU CSB-EP005431HU CSB-BP005431HU CSB-MP005431HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

CIDEA Protein - abx163643 from Abbexa Category Protein Species Human

Cell death activator CIDE-A (CIDEA), Recombinant Protein - MBS1261219 from MyBioSource Category Protein Prices $970.00, $970.00, $1,195.00, $1,195.00, $1,460.00, $1,460.00, $1,925.00, $1,925.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

Cell Death Inducing DFFA Like Effector A, Recombinant Protein - MBS2030399 from MyBioSource Category Protein Prices $195.00, $420.00, $645.00 Sizes 10 µg, 50 µg, 100 µg Source Prokaryotic expression Species Human

Synthetic CIDE-A CT (aa 200-214) - PX016BP from Cell Science Prices $170.00 Sizes 50 μg

Synthetic CIDE-A CT (aa 200-217) - PX015BP from Cell Science Prices $170.00 Sizes 50 μg

CIDEA Peptide, Human - M34GP03174H from Creative Peptides Category Peptide Source Synthetic. Species Human

CIDEA Recombinant Protein (OPCD02220) - OPCD02220 from Aviva Systems Biology Category Protein Source E.coli Species Human

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