PSMB5

Gene Symbol PSMB5
Entrez Gene 5693
Alt Symbol LMPX, MB1, X
Species Human
Gene Type protein-coding
Description proteasome (prosome, macropain) subunit, beta type, 5
Other Description PSX large multifunctional protease X|macropain epsilon chain|multicatalytic endopeptidase complex epsilon chain|proteasome beta 5 subunit|proteasome catalytic subunit 3|proteasome chain 6|proteasome epsilon chain|proteasome subunit MB1|proteasome subunit X|proteasome subunit beta type-5|proteasome subunit, beta type, 5
Swissprots Q86T01 Q9TNN9 B2R4N9 Q16242 P28074 B4DUM9 E9PAV2 Q6PEW2 Q7Z3B5 D3DS43
Accessions CAA64838 EAW66193 EAW66194 EAW66195 P28074 AK225888 AK300714 BAG62391 AK311895 BAG34836 BC057840 AAH57840 BC107720 AAI07721 BT006777 AAP35423 BU539357 BU632351 BX248299 CAD62626 BX538001 CAD97956 CD048996 HQ448536 ADQ33015 S74378 AAB33092 XM_005267871 XP_005267928 NM_001130725 NP_001124197 NM_001144932 NP_001138404 NM_002797 NP_002788
Function The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This unit is responsible of the chymotrypsin-like activity of the proteasome and is one of the principal target of the proteasome inhibitor bortezomib. May catalyze basal processing of intracellular antigens. Plays a role in the protection against oxidative damage through the Nrf2-ARE pathway (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm. Nucleus.
Top Pathways Proteasome

PSMB5 (D1H6B) Rabbit mAb - 12919 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D1H6B
Western blot analysis of extracts from various cell lines using PSMB5 (D1H6B) Rabbit mAb.

PSMB5 Antibody - 11903 from Cell Signaling Technology

Prices $239.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from various cell lines using PSMB5 Antibody.

20S Proteasome β5 (C-19) - sc-55009 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
20S Proteasome β5 (C-19): sc-55009. Immunoperoxi-dase staining of formalin fixed, paraffin-embedded human cerebellum tissue showing cytoplasmic and nuclear staining of Purkinje cells and neuropil staining in granular and molecular layers.

20S Proteasome β5 (K-19) - sc-55012 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-PSMB5 antibody - ab89134 from Abcam

Prices $376.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-PSMB5 antibody (ab89134) at 1 µg/ml + Human liver lysate at 50 µgdeveloped using the ECL technique

Anti-PSMB5 antibody - ab140521 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-PSMB5 antibody (ab140521) at 0.1 µg/mlLane 1 : 293T whole cell lysate at 50 µgLane 2 : 293T whole cell lysate at 15 µgLane 3 : HeLa whole cell lysate at 50 µgLane 4 : Jurkat whole cell lysate at 50 µgdeveloped using the ECL technique

Anti-PSMB5 antibody - ab167341 from Abcam

Prices $376.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-PSMB5 antibody (ab167341) at 1 µg/mlLane 1 : PSMB5 transfected 293T cell line lysateLane 2 : Non-transfected 293T cell line lysateLysates/proteins at 15 µl per lane.

Anti-PSMB5 antibody - ab111263 from Abcam

Prices $376.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Formalin-Fixed, Paraffin-Embedded Human Brain cerebellum tissue stained using ab111263 at a concentration of 3.75 µg/ml.

Anti-PSMB5 antibody - C-terminal - ab137771 from Abcam

Prices $384.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-PSMB5 antibody - C-terminal (ab137771) at 1/1000 dilutionLane 1 : A431 cell lysateLane 2 : H1299 cell lysateLysates/proteins at 30 µg per lane.

Anti-PSMB5 Antibody (aa234-263) - LS-C162231 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
PSMB5 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human skin tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

Anti-PSMB5 Antibody IHC-plus™ - LS-B3830 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-PSMB5 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3830 concentration 3.75 ug/ml.

Anti-PSMB5 Antibody (C-Terminus) - LS-C86225 from LifeSpan Bioscience

Prices $755.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PSMB5 Antibody (N-Terminus) - LS-C46923 from LifeSpan Bioscience

Prices $275.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PSMB5 Antibody (aa234-263, Biotin) - LS-C267287 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PSMB5 Antibody (aa234-263, AP) - LS-C267286 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PSMB5 Antibody (aa234-263, APC) - LS-C267288 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PSMB5 Antibody (aa234-263, PE) - LS-C267290 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PSMB5 Antibody (aa234-263, FITC) - LS-C267289 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PSMB5 Antibody (aa234-263, Azide-free, HRP) - LS-C267291 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PSMB5 Antibody (aa234-263) - LS-C330029 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PSMB5 Antibody - LS-C341394 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PSMB5 Antibody - LS-C343798 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-PSMB5 Antibody (aa72-121) - LS-C111925 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
PSMB5 antibody LS-C111925 Western blot of MCF7 cell lysate.

Anti-PSMB5 Antibody (aa213-263) - LS-C290496 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human PSMB5 by Western Blot of Immunoprecipitates. Samples: Whole cell lysate (1 mg for IP; 20% of IP loaded) from 293T cells. Antibodies: Affinity purified rabbit anti-PSMB5 antibody used for IP at 6 ug/mg lysate. For blotting immunoprecipitated PSMB5, was used at 1 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.

Anti-PSMB5 Antibody - LS-C331798 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry of paraffin-embedded human stomach using PSMB5 antibody at dilution of 1:200 (x400 lens)
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