Gene Symbol | TRIT1 |
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Entrez Gene | 54802 |
Alt Symbol | IPT, MOD5 |
Species | Human |
Gene Type | protein-coding |
Description | tRNA isopentenyltransferase 1 |
Other Description | IPP transferase|IPPT|IPTase|hGRO1|isopentenyl-diphosphate:tRNA isopentenyltransferase|tRNA dimethylallyltransferase, mitochondrial|tRNA isopentenylpyrophosphate transferase |
Swissprots | Q3T7B5 Q9NXT7 Q5QPK5 Q96L45 Q96FJ3 Q6IAC9 Q9H3H1 Q5QPK6 A1A4X7 |
Accessions | EAX07252 EAX07253 Q9H3H1 AF074918 AAG31324 AK000068 BAA90923 AK074222 AK223478 BAD97198 AK296453 BAG59101 AK304759 BAG65514 AK307910 AY052768 AAL14107 AY303390 AAP60111 AY702933 AAW63394 AY702934 AAW63395 AY702935 AAW63396 AY702936 AAW63397 AY702937 AAW63398 AY702938 AAW63399 AY702939 AAW63400 AY702940 AAW63401 AY702941 AAW63402 AY702942 AAW63403 AY702943 AAW63404 AY702944 AAW63405 AY702945 AAW63406 AY702946 AAW63407 AY702947 BC010741 AAH10741 BC107569 AAI07570 BC128155 AAI28156 BC128156 AAI28157 CR457226 CAG33507 DA031689 XM_005270954 XP_005271011 XM_006710706 XP_006710769 XR_246278 XR_946671 XR_946672 NM_017646 NP_060116 |
Function | Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 of both cytosolic and mitochondrial tRNAs, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A). {ECO:0000269|PubMed:11111046}. |
Subcellular Location | Isoform 5: Cytoplasm {ECO:0000305}. |
MOD5 CRISPR/Cas9 KO Plasmid (h) - sc-412338 from Santa Cruz Biotechnology
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MOD5 HDR Plasmid (h) - sc-412338-HDR from Santa Cruz Biotechnology
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MOD5 Double Nickase Plasmid (h) - sc-412338-NIC from Santa Cruz Biotechnology
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MOD5 Double Nickase Plasmid (h2) - sc-412338-NIC-2 from Santa Cruz Biotechnology
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MOD5 CRISPR Activation Plasmid (h) - sc-412338-ACT from Santa Cruz Biotechnology
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MOD5 CRISPR Activation Plasmid (h2) - sc-412338-ACT-2 from Santa Cruz Biotechnology
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MOD5 Lentiviral Activation Particles (h) - sc-412338-LAC from Santa Cruz Biotechnology
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MOD5 Lentiviral Activation Particles (h2) - sc-412338-LAC-2 from Santa Cruz Biotechnology
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MOD5 siRNA (h) - sc-62631 from Santa Cruz Biotechnology
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MOD5 shRNA Plasmid (h) - sc-62631-SH from Santa Cruz Biotechnology
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MOD5 shRNA (h) Lentiviral Particles - sc-62631-V from Santa Cruz Biotechnology
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TRIT1 RNAi - H00054802-R01 from Novus Biologicals
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MISSION® esiRNA - EHU072521 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN22033 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22033 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR05852 from Sigma-Aldrich
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TRIT1 siRNA (Human) - CRJ0226 from Cohesion Biosciences
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TRIT1 - MBS8227054 from MyBioSource
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shRNA set against Human TRIT1 (NM_017646.4) - SHH435244 from Creative biogene
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Human TRIT1 siRNA - orb270727 from Biorbyt
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TRIT1 shRNA Plasmid (Human) - CHJ0226 from Cohesion Biosciences
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TRIT1 miRNA 3'UTR clone - MiUTR3H-16408 from Creative biogene
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