Gene Symbol | BAMBI |
---|---|
Entrez Gene | 25805 |
Alt Symbol | NMA |
Species | Human |
Gene Type | protein-coding |
Description | BMP and activin membrane-bound inhibitor |
Other Description | BMP and activin membrane-bound inhibitor homolog|non-metastatic gene A protein|putative transmembrane protein NMA |
Swissprots | Q13145 |
Accessions | AAR02414 CAB89152 EAW86030 EAW86031 Q13145 AI680996 AK223065 BAD96785 AK290639 BAF83328 BC019252 AAH19252 BQ640107 BT006820 AAP35466 U23070 AAC50435 NM_012342 NP_036474 |
Function | Negatively regulates TGF-beta signaling. |
Subcellular Location | Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. |
Tissue Specificity | High expression in kidney medulla, placenta and spleen; low in kidney cortex, liver, prostate and gut. Not expressed in normal skin, expression is high in melanocytes and in 3 out of 11 melanoma metastases tested. |
Top Pathways | Wnt signaling pathway, TGF-beta signaling pathway |