Gene Symbol | BAMBI |
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Entrez Gene | 25805 |
Alt Symbol | NMA |
Species | Human |
Gene Type | protein-coding |
Description | BMP and activin membrane-bound inhibitor |
Other Description | BMP and activin membrane-bound inhibitor homolog|non-metastatic gene A protein|putative transmembrane protein NMA |
Swissprots | Q13145 |
Accessions | AAR02414 CAB89152 EAW86030 EAW86031 Q13145 AI680996 AK223065 BAD96785 AK290639 BAF83328 BC019252 AAH19252 BQ640107 BT006820 AAP35466 U23070 AAC50435 NM_012342 NP_036474 |
Function | Negatively regulates TGF-beta signaling. |
Subcellular Location | Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. |
Tissue Specificity | High expression in kidney medulla, placenta and spleen; low in kidney cortex, liver, prostate and gut. Not expressed in normal skin, expression is high in melanocytes and in 3 out of 11 melanoma metastases tested. |
Top Pathways | Wnt signaling pathway, TGF-beta signaling pathway |
BAMBI CRISPR/Cas9 KO Plasmid (h) - sc-403701 from Santa Cruz Biotechnology
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BAMBI HDR Plasmid (h) - sc-403701-HDR from Santa Cruz Biotechnology
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BAMBI Double Nickase Plasmid (h) - sc-403701-NIC from Santa Cruz Biotechnology
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BAMBI Double Nickase Plasmid (h2) - sc-403701-NIC-2 from Santa Cruz Biotechnology
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BAMBI CRISPR Activation Plasmid (h) - sc-403701-ACT from Santa Cruz Biotechnology
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BAMBI CRISPR Activation Plasmid (h2) - sc-403701-ACT-2 from Santa Cruz Biotechnology
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BAMBI Lentiviral Activation Particles (h) - sc-403701-LAC from Santa Cruz Biotechnology
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BAMBI Lentiviral Activation Particles (h2) - sc-403701-LAC-2 from Santa Cruz Biotechnology
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BAMBI siRNA (h) - sc-60243 from Santa Cruz Biotechnology
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BAMBI shRNA Plasmid (h) - sc-60243-SH from Santa Cruz Biotechnology
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BAMBI shRNA (h) Lentiviral Particles - sc-60243-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU009931 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN3855 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3855 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR05389 from Sigma-Aldrich
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BAMBI siRNA (Human) - CRH8509 from Cohesion Biosciences
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BAMBI/NMA RNAi - H00025805-R01 from Novus Biologicals
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BAMBI - MBS8217315 from MyBioSource
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shRNA set against Human BAMBI (NM_012342.2) - SHH244806 from Creative biogene
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shRNA set against Human BAMBI(NM_012342.2) - SHG034001 from Creative biogene
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BAMBI shRNA Plasmid (Human) - CHH8509 from Cohesion Biosciences
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BAMBI miRNA 3'UTR clone - MiUTR1H-00800 from Creative biogene
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