| Gene Symbol |
SPINK9
|
| Entrez Gene |
643394
|
| Alt Symbol |
LEKTI2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
serine peptidase inhibitor, Kazal type 9
|
| Other Description |
lymphoepithelial Kazal-type-related inhibitor 2|serine protease inhibitor Kazal type 9|serine protease inhibitor Kazal-type 9
|
| Swissprots |
B2RPN9 Q5DT21
|
| Accessions |
Q5DT21 AY396740 AAR91618 BC137530 AAI37531 BC137531 AAI37532 NM_001040433 NP_001035523
|
| Function |
Serine protease inhibitor which specifically inhibits KLK5. May contribute to the regulation of the desquamation process in skin by inhibiting KLK5. {ECO:0000269|PubMed:19190773, ECO:0000269|PubMed:19194479}.
|
| Subcellular Location |
Secreted {ECO:0000305}.
|
| Tissue Specificity |
Skin. Highly expressed at sites of hyperkeratosis. Also detected in thymus, tonsils, testis, pancreas, liver, placenta and brain. Expressed at stratum granulosum and stratum corneum at palmar and plantar sites (at protein level). {ECO:0000269|PubMed:19190773, ECO:0000269|PubMed:19194479}.
|