Gene Symbol | SPINK9 |
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Entrez Gene | 643394 |
Alt Symbol | LEKTI2 |
Species | Human |
Gene Type | protein-coding |
Description | serine peptidase inhibitor, Kazal type 9 |
Other Description | lymphoepithelial Kazal-type-related inhibitor 2|serine protease inhibitor Kazal type 9|serine protease inhibitor Kazal-type 9 |
Swissprots | B2RPN9 Q5DT21 |
Accessions | Q5DT21 AY396740 AAR91618 BC137530 AAI37531 BC137531 AAI37532 NM_001040433 NP_001035523 |
Function | Serine protease inhibitor which specifically inhibits KLK5. May contribute to the regulation of the desquamation process in skin by inhibiting KLK5. {ECO:0000269|PubMed:19190773, ECO:0000269|PubMed:19194479}. |
Subcellular Location | Secreted {ECO:0000305}. |
Tissue Specificity | Skin. Highly expressed at sites of hyperkeratosis. Also detected in thymus, tonsils, testis, pancreas, liver, placenta and brain. Expressed at stratum granulosum and stratum corneum at palmar and plantar sites (at protein level). {ECO:0000269|PubMed:19190773, ECO:0000269|PubMed:19194479}. |
SPINK9 CRISPR/Cas9 KO Plasmid (h) - sc-416784 from Santa Cruz Biotechnology
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SPINK9 HDR Plasmid (h) - sc-416784-HDR from Santa Cruz Biotechnology
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SPINK9 Double Nickase Plasmid (h) - sc-416784-NIC from Santa Cruz Biotechnology
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SPINK9 Double Nickase Plasmid (h2) - sc-416784-NIC-2 from Santa Cruz Biotechnology
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SPINK9 CRISPR Activation Plasmid (h) - sc-416784-ACT from Santa Cruz Biotechnology
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SPINK9 CRISPR Activation Plasmid (h2) - sc-416784-ACT-2 from Santa Cruz Biotechnology
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SPINK9 Lentiviral Activation Particles (h) - sc-416784-LAC from Santa Cruz Biotechnology
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SPINK9 Lentiviral Activation Particles (h2) - sc-416784-LAC-2 from Santa Cruz Biotechnology
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SPINK9 siRNA (h) - sc-91686 from Santa Cruz Biotechnology
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SPINK9 shRNA Plasmid (h) - sc-91686-SH from Santa Cruz Biotechnology
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SPINK9 shRNA (h) Lentiviral Particles - sc-91686-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU102361 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN20487 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20487 from Sigma-Aldrich
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SPINK9 siRNA (Human) - CRJ8455 from Cohesion Biosciences
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SPINK9 - MBS8233635 from MyBioSource
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shRNA set against Human SPINK9 (NM_001040433.1) - SHH416844 from Creative biogene
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SPINK9 shRNA Plasmid (Human) - CHJ8455 from Cohesion Biosciences
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SPINK9 miRNA 3'UTR clone - MiUTR1H-09849 from Creative biogene
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