CELF2

Gene Symbol	CELF2
Entrez Gene	10659
Alt Symbol	BRUNOL3, CUGBP2, ETR-3, ETR3, NAPOR
Species	Human
Gene Type	protein-coding
Description	CUGBP, Elav-like family member 2
Other Description	CELF-2|CUG triplet repeat RNA-binding protein 2|CUG-BP- and ETR-3-like factor 2|CUG-BP2|CUGBP Elav-like family member 2|ELAV-type RNA-binding protein 3|RNA-binding protein BRUNOL-3|bruno-like protein 3|neuroblastoma apoptosis-related RNA-binding protein
Swissprots	Q9UL67 Q7KYU4 Q96RQ5 Q92950 Q96NW9 Q96RQ6 B7ZAN9 Q8N499 O95319
Accessions	AAK72223 AAK72224 AAK92699 EAW86346 EAW86347 EAW86348 EAW86349 EAW86350 O95319 AA595891 AF036956 AAD02074 AF086447 AF090693 AAD13760 AF090694 AAD13761 AF432906 AAL27627 AK293164 BAG56708 AK295511 BAG58428 AK297313 BAG59778 AK297380 BAG59822 AK299548 BAG61493 AK299983 BAG61804 AK299992 BAG61812 AK302681 BAG63913 AK304216 BAG65088 AK310038 AK314087 BAG36783 AK316354 BAH14725 AW965523 BC036391 AAH36391 BC050635 BE275530 BI914655 BM699598 BP229421 BP362205 BQ213648 BU173199 CD556770 CN356737 CR936676 CR976278 DA310511 DA819821 DB478862 U69546 AAB09040 XM_005252354 XP_005252411 XM_005252357 XP_005252414 XM_005252358 XP_005252415 XM_006717369 XP_006717432 XM_006717370 XP_006717433 XM_006717371 XP_006717434 XM_006717373 XP_006717436 XM_006717374 XP_006717437 XM_006717375 XP_006717438 XM_011519294 XP_011517596 XM_011519295 XP_011517597 XM_011519296 XP_011517598 XM_011519297 XP_011517599 XM_011519298 XP_011517600 XM_011519299 XP_011517601 NM_001025076 NP_001020247 NM_001025077 NP_001020248 NM_001083591 NP_001077060 NM_006561 NP_006552
Function	RNA-binding protein implicated in the regulation of several post-transcriptional events. Involved in pre-mRNA alternative splicing, mRNA translation and stability. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of TNNT2 in embryonic, but not adult, skeletal muscle. Activates TNNT2 exon 5 inclusion by antagonizing the repressive effect of PTB. Acts as both an activator and repressor of a pair of coregulated exons: promotes inclusion of the smooth muscle (SM) exon but exclusion of the non-muscle (NM) exon in actinin pre-mRNAs. Promotes inclusion of exonS 21 and exclusion of exon 5 of the NMDA receptor R1 pre- mRNA. Involved in the apoB RNA editing activity. Increases COX2 mRNA stability and inhibits COX2 mRNA translation in epithelial cells after radiation injury (By similarity). Modulates the cellular apoptosis program by regulating COX2-mediated prostagl
Subcellular Location	Nucleus. Cytoplasm. Note=Accumulates in the cytoplasm after ionizing radiation (By similarity). Colocalizes with APOBEC1 and A1CF. RNA-binding activity is detected in both nuclear and cytoplasmic compartments. {ECO:0000250}.
Tissue Specificity	Expressed in frontal cortex. Isoform 1 is expressed in brain and lung. Isoform 2 is expressed in heart, brain, placenta, lung, liver, kidney, skeletal muscle and pancreas. Isoform 4 is expressed in heart, lung, skeletal muscle, kidney and pancreas. {ECO:0000269|PubMed:10524244, ECO:0000269|PubMed:10893231, ECO:0000269|PubMed:11158314, ECO:0000269|PubMed:11414768, ECO:0000269|PubMed:16862542}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

CUG-BP2 (1H2) - sc-47731 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Mouse Clonality Monoclonal

CUG-BP2 (N-15) - sc-27087 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Anti-Elav-type RNA-binding protein ETR3 antibody - ab93441 from Abcam Prices $370.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-Elav-type RNA-binding protein ETR3 antibody - ab130727 from Abcam Prices $370.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-Elav-type RNA-binding protein ETR3 antibody [EPR13374] - ab179447 from Abcam Prices $357.00 Sizes 100 µl Host Rabbit Clonality Monoclonal Clone EPR13374

Anti-Elav-type RNA-binding protein ETR3 antibody [EPR13374-2] - ab186430 from Abcam Prices $357.00 Sizes 100 µl Host Rabbit Clonality Monoclonal Clone EPR13374-2

Anti-CELF2 / CUGBP2 Antibody (C-Terminus) - LS-C2656 from LifeSpan Bioscience Prices $335.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-CELF2 / CUGBP2 Antibody (C-Terminus) - LS-C23308 from LifeSpan Bioscience Prices $325.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-CELF2 / CUGBP2 Antibody (C-Terminus) - LS-C40586 from LifeSpan Bioscience Prices $275.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-CELF2 / CUGBP2 Antibody (aa480-508, AP) - LS-C213473 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-CELF2 / CUGBP2 Antibody (aa480-508, APC) - LS-C213474 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-CELF2 / CUGBP2 Antibody (aa480-508, FITC) - LS-C213476 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-CELF2 / CUGBP2 Antibody (aa480-508, Biotin) - LS-C213475 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-CELF2 / CUGBP2 Antibody (aa480-508, Azide-free, HRP) - LS-C213477 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-CELF2 / CUGBP2 Antibody (aa480-508, PE) - LS-C213478 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-CELF2 / CUGBP2 Antibody - LS-C310032 from LifeSpan Bioscience Prices $475.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-CELF2 / CUGBP2 Antibody (aa73-122) - LS-C31676 from LifeSpan Bioscience Prices $325.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-CELF2 / CUGBP2 Antibody (aa480-508) - LS-C320685 from LifeSpan Bioscience Prices $345.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-CELF2 / CUGBP2 Antibody (aa112-161) - LS-C80313 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-CELF2 / CUGBP2 Antibody - LS-C334461 from LifeSpan Bioscience Prices $315.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-CELF2 / CUGBP2 Antibody (N-Terminus) IHC-plus™ - LS-B6819 from LifeSpan Bioscience Prices $450.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-CELF2 / CUGBP2 Antibody (aa480-508) IHC-plus™ - LS-B10687 from LifeSpan Bioscience Prices $395.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

CUGBP2 Antibody - NBP2-16035 from Novus Biologicals Prices $329.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

CUGBP2 Antibody - NBP2-16034 from Novus Biologicals Prices $329.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

CUGBP2 Antibody - NBP1-57376 from Novus Biologicals Prices $299.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

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