Gene Symbol |
Lcor
|
Entrez Gene |
212391
|
Alt Symbol |
3110023F06Rik, A630025C20Rik, Mlr2, mKIAA1795
|
Species |
Mouse
|
Gene Type |
protein-coding
|
Description |
ligand dependent nuclear receptor corepressor
|
Other Description |
Mblk1-related protein-2|ligand-dependent corepressor|mblk1-related protein 2|transcription factor MLR2
|
Swissprots |
Q3U302 Q5CZW7 Q80VA8 Q6ZPI3 Q8C9Q0 Q8BGT2
|
Accessions |
EDL41857 Q6ZPI3 AB076079 BAC20955 AK014072 AK034834 AK041090 BAC30816 AK041621 BAC31007 AK054275 AK077424 AK129442 BAC98252 AK155007 BAE32988 AK171159 AK171287 BC050068 AAH50068 BC090652 AAH90652 BC099938 AAH99938 DQ700429 XM_006526848 XP_006526911 XM_006526849 XP_006526912 XM_006526850 XP_006526913 XM_011247214 XP_011245516 XM_011247215 XP_011245517 XM_011247216 XP_011245518 XM_011247217 XP_011245519 XM_011247218 XP_011245520 XR_877669 XR_877670 NM_172154 NP_742166
|
Function |
Repressor of ligand-dependent transcription activation by various nuclear repressors. Repressor of ligand-dependent transcription activation by ESR1, ESR2, NR3C1, PGR, RARA, RARB, RARG, RXRA and VDR (By similarity). May act as transcription activator that binds DNA elements with the sequence 5'- CCCTATCGATCGATCTCTACCT-3'. {ECO:0000250, ECO:0000269|PubMed:12560079}.
|
Subcellular Location |
Nucleus {ECO:0000255|PROSITE- ProRule:PRU00320}.
|
Tissue Specificity |
Detected in heart and kidney. {ECO:0000269|PubMed:12560079}.
|