Gene Symbol | Lcor |
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Entrez Gene | 212391 |
Alt Symbol | 3110023F06Rik, A630025C20Rik, Mlr2, mKIAA1795 |
Species | Mouse |
Gene Type | protein-coding |
Description | ligand dependent nuclear receptor corepressor |
Other Description | Mblk1-related protein-2|ligand-dependent corepressor|mblk1-related protein 2|transcription factor MLR2 |
Swissprots | Q3U302 Q5CZW7 Q80VA8 Q6ZPI3 Q8C9Q0 Q8BGT2 |
Accessions | EDL41857 Q6ZPI3 AB076079 BAC20955 AK014072 AK034834 AK041090 BAC30816 AK041621 BAC31007 AK054275 AK077424 AK129442 BAC98252 AK155007 BAE32988 AK171159 AK171287 BC050068 AAH50068 BC090652 AAH90652 BC099938 AAH99938 DQ700429 XM_006526848 XP_006526911 XM_006526849 XP_006526912 XM_006526850 XP_006526913 XM_011247214 XP_011245516 XM_011247215 XP_011245517 XM_011247216 XP_011245518 XM_011247217 XP_011245519 XM_011247218 XP_011245520 XR_877669 XR_877670 NM_172154 NP_742166 |
Function | Repressor of ligand-dependent transcription activation by various nuclear repressors. Repressor of ligand-dependent transcription activation by ESR1, ESR2, NR3C1, PGR, RARA, RARB, RARG, RXRA and VDR (By similarity). May act as transcription activator that binds DNA elements with the sequence 5'- CCCTATCGATCGATCTCTACCT-3'. {ECO:0000250, ECO:0000269|PubMed:12560079}. |
Subcellular Location | Nucleus {ECO:0000255|PROSITE- ProRule:PRU00320}. |
Tissue Specificity | Detected in heart and kidney. {ECO:0000269|PubMed:12560079}. |
LCOR CRISPR/Cas9 KO Plasmid (m) - sc-431795 from Santa Cruz Biotechnology
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LCOR HDR Plasmid (m) - sc-431795-HDR from Santa Cruz Biotechnology
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LCOR Double Nickase Plasmid (m) - sc-431795-NIC from Santa Cruz Biotechnology
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LCOR Double Nickase Plasmid (m2) - sc-431795-NIC-2 from Santa Cruz Biotechnology
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LCOR CRISPR Activation Plasmid (m) - sc-431795-ACT from Santa Cruz Biotechnology
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LCOR CRISPR Activation Plasmid (m2) - sc-431795-ACT-2 from Santa Cruz Biotechnology
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LCOR Lentiviral Activation Particles (m) - sc-431795-LAC from Santa Cruz Biotechnology
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LCOR Lentiviral Activation Particles (m2) - sc-431795-LAC-2 from Santa Cruz Biotechnology
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LCOR siRNA (m) - sc-146685 from Santa Cruz Biotechnology
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LCOR shRNA Plasmid (m) - sc-146685-SH from Santa Cruz Biotechnology
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LCOR shRNA (m) Lentiviral Particles - sc-146685-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN34682 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND34682 from Sigma-Aldrich
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LCOR siRNA (Mouse) - CRN1774 from Cohesion Biosciences
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shRNA set against Mouse LCOR (NM_172154.4) - SHH329171 from Creative biogene
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shRNA set against Mouse Lcor(NM_172154.4) - SHH144731 from Creative biogene
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Mouse LCOR siRNA - orb291249 from Biorbyt
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LCOR shRNA Plasmid (Mouse) - CHN1774 from Cohesion Biosciences
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LCOR miRNA 3'UTR clone - MiUTR1M-06567 from Creative biogene
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