Gene Symbol | MSRB3 |
---|---|
Entrez Gene | 253827 |
Alt Symbol | DFNB74 |
Species | Human |
Gene Type | protein-coding |
Description | methionine sulfoxide reductase B3 |
Other Description | methionine-R-sulfoxide reductase B3|methionine-R-sulfoxide reductase B3, mitochondrial |
Swissprots | B4DR19 B7ZAQ0 Q8IXL7 Q6UXS2 |
Accessions | EAW97151 Q8IXL7 AK094185 AK122602 AK293084 BAF85773 AK299065 BAG61131 AK316365 BAH14736 AL833622 AY358229 AAQ88596 BC040053 AAH40053 BX500552 BX640871 CAE45929 BX648776 CAI46018 DC357690 DQ786269 HQ448601 ADQ33079 NM_001031679 NP_001026849 NM_001193460 NP_001180389 NM_001193461 NP_001180390 NM_198080 NP_932346 |
Function | Catalyzes the reduction of free and protein-bound methionine sulfoxide to methionine. Isoform 2 is essential for hearing. {ECO:0000269|PubMed:14699060, ECO:0000269|PubMed:21185009}. |
Subcellular Location | Isoform 1: Endoplasmic reticulum. |
Tissue Specificity | Widely expressed. {ECO:0000269|PubMed:15914630, ECO:0000269|PubMed:21185009}. |