Gene Symbol | MSRB3 |
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Entrez Gene | 253827 |
Alt Symbol | DFNB74 |
Species | Human |
Gene Type | protein-coding |
Description | methionine sulfoxide reductase B3 |
Other Description | methionine-R-sulfoxide reductase B3|methionine-R-sulfoxide reductase B3, mitochondrial |
Swissprots | B4DR19 B7ZAQ0 Q8IXL7 Q6UXS2 |
Accessions | EAW97151 Q8IXL7 AK094185 AK122602 AK293084 BAF85773 AK299065 BAG61131 AK316365 BAH14736 AL833622 AY358229 AAQ88596 BC040053 AAH40053 BX500552 BX640871 CAE45929 BX648776 CAI46018 DC357690 DQ786269 HQ448601 ADQ33079 NM_001031679 NP_001026849 NM_001193460 NP_001180389 NM_001193461 NP_001180390 NM_198080 NP_932346 |
Function | Catalyzes the reduction of free and protein-bound methionine sulfoxide to methionine. Isoform 2 is essential for hearing. {ECO:0000269|PubMed:14699060, ECO:0000269|PubMed:21185009}. |
Subcellular Location | Isoform 1: Endoplasmic reticulum. |
Tissue Specificity | Widely expressed. {ECO:0000269|PubMed:15914630, ECO:0000269|PubMed:21185009}. |
MsrB3 CRISPR/Cas9 KO Plasmid (h) - sc-410394 from Santa Cruz Biotechnology
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MsrB3 HDR Plasmid (h) - sc-410394-HDR from Santa Cruz Biotechnology
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MsrB3 Double Nickase Plasmid (h) - sc-410394-NIC from Santa Cruz Biotechnology
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MsrB3 Double Nickase Plasmid (h2) - sc-410394-NIC-2 from Santa Cruz Biotechnology
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MsrB3 CRISPR Activation Plasmid (h) - sc-410394-ACT from Santa Cruz Biotechnology
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MsrB3 CRISPR Activation Plasmid (h2) - sc-410394-ACT-2 from Santa Cruz Biotechnology
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MsrB3 Lentiviral Activation Particles (h) - sc-410394-LAC from Santa Cruz Biotechnology
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MsrB3 Lentiviral Activation Particles (h2) - sc-410394-LAC-2 from Santa Cruz Biotechnology
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MsrB3 siRNA (h) - sc-95827 from Santa Cruz Biotechnology
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MsrB3 shRNA Plasmid (h) - sc-95827-SH from Santa Cruz Biotechnology
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MsrB3 shRNA (h) Lentiviral Particles - sc-95827-V from Santa Cruz Biotechnology
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MSRB3 RNAi - H00253827-R02 from Novus Biologicals
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MSRB3 RNAi - H00253827-R01 from Novus Biologicals
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MISSION® esiRNA - EHU083261 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN14660 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND14660 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR14165 from Sigma-Aldrich
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MSRB3 siRNA (Human) - CRJ6655 from Cohesion Biosciences
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shRNA set against Human MSRB (NM_198080.3) - SHH345820 from Creative biogene
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MSRB3 shRNA Plasmid (Human) - CHJ6655 from Cohesion Biosciences
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MSRB3 miRNA 3'UTR clone - MiUTR4H-TG05690 from Creative biogene
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