| Gene Symbol | Dntt |
|---|---|
| Entrez Gene | 21673 |
| Alt Symbol | Tdt |
| Species | Mouse |
| Gene Type | protein-coding |
| Description | deoxynucleotidyltransferase, terminal |
| Other Description | DNA nucleotidylexotransferase|terminal addition enzyme|terminal deoxynucleotidyl transferase |
| Swissprots | Q99PD1 P09838 Q99PD0 |
| Accessions | AAK01196 EDL41849 P09838 AF316014 AAK07884 AF316015 AAK07885 AK039804 AK087978 BAC40071 AK088709 BAC40518 AK134009 BAE21978 BC027634 BC148334 AAI48335 BX639078 M26145 AAA74592 M26149 X04123 CAA27735 X68670 CAA48634 NM_001043228 NP_001036693 NM_009345 NP_033371 |
| Function | Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator. One of the in vivo functions of this enzyme is the addition of nucleotides at the junction (N region) of rearranged Ig heavy chain and T-cell receptor gene segments during the maturation of B- and T-cells. |
| Subcellular Location | Isoform TDT-S: Nucleus. |
| Top Pathways | Hematopoietic cell lineage, Non-homologous end-joining |