| Gene Symbol |
LPPR4
|
| Entrez Gene |
9890
|
| Alt Symbol |
LPR4, PHP1, PRG-1, PRG1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
lipid phosphate phosphatase-related protein type 4
|
| Other Description |
brain-specific phosphatidic acid phosphatase-like protein 1|plasticity related gene 1|plasticity-related gene 1 protein
|
| Swissprots |
Q96MP0 Q5T9R9 Q8N3F1 Q7Z2D5 O75043 E7EPS1 Q86XQ5
|
| Accessions |
EAW72991 EAW72992 Q7Z2D5 AB007924 BAA32300 AF357013 AAO85400 AF541281 AAP57770 AK291369 BAF84058 AK300361 BAG62101 AL834390 CAD39052 AY304518 AAP72155 BC041386 AAH41386 BC042963 AAH42963 BC148348 AAI48349 XM_011542498 XP_011540800 NM_014839 NP_055654 NM_001166252 NP_001159724
|
| Function |
Hydrolyzes lysophosphatidic acid (LPA). Facilitates axonal outgrowth during development and regenerative sprouting. In the outgrowing axons acts as an ecto-enzyme and attenuates phospholipid-induced axon collapse in neurons and facilitates outgrowth in the hippocampus. {ECO:0000269|PubMed:12730698}.
|
| Subcellular Location |
Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
|
| Tissue Specificity |
Specifically expressed in neurons. {ECO:0000269|PubMed:12730698}.
|